-transparent.png){kind=logo}
Abnormalities of the short arm of chromosome 12 are nonrandom events in T cell prolymphocytic leukemia (T-PLL). Fluorescence in situ hybridization (FISH) studies were performed in three patients with T-PLL and one patient with T cell peripheral lymphoma and rearrangement of 12p. Whereas the rearrangements of 12p were different in the four patients, a breakpoint centromeric to the ETV6 gene was present in the three T-PLL patients. In addition, loss of heterozygosity for a chromosomal segment telomeric to ETV6 with loss of the RAD52 locus was also shown by FISH studies. In contrast, the breakpoint was telomeric to ETV6 in the patient with peripheral lymphoma.
Related Publications
F Salomon-Nguyen, and
F Brizard, and
M Le Coniat, and
I Radford, and
R Berger, and
A Brizard
January 1986,
Cancer genetics and cytogenetics,
F Salomon-Nguyen, and
F Brizard, and
M Le Coniat, and
I Radford, and
R Berger, and
A Brizard
January 2004,
Acta haematologica,
F Salomon-Nguyen, and
F Brizard, and
M Le Coniat, and
I Radford, and
R Berger, and
A Brizard
May 2017,
American journal of hematology,
F Salomon-Nguyen, and
F Brizard, and
M Le Coniat, and
I Radford, and
R Berger, and
A Brizard
August 1983,
Cancer genetics and cytogenetics,
F Salomon-Nguyen, and
F Brizard, and
M Le Coniat, and
I Radford, and
R Berger, and
A Brizard
January 2013,
Proceedings (Baylor University. Medical Center),
F Salomon-Nguyen, and
F Brizard, and
M Le Coniat, and
I Radford, and
R Berger, and
A Brizard
April 2017,
Hematology/oncology clinics of North America,
F Salomon-Nguyen, and
F Brizard, and
M Le Coniat, and
I Radford, and
R Berger, and
A Brizard
January 1998,
Cancer control : journal of the Moffitt Cancer Center,
F Salomon-Nguyen, and
F Brizard, and
M Le Coniat, and
I Radford, and
R Berger, and
A Brizard
January 2006,
Medical oncology (Northwood, London, England),
F Salomon-Nguyen, and
F Brizard, and
M Le Coniat, and
I Radford, and
R Berger, and
A Brizard
January 1998,
Ryoikibetsu shokogun shirizu,
F Salomon-Nguyen, and
F Brizard, and
M Le Coniat, and
I Radford, and
R Berger, and
A Brizard
March 2009,
Expert review of anticancer therapy,
