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In 54 epileptic patients (28 females and 26 males) aged 21-48, serum copper (Cu) and ceruloplasmin (Crl) concentrations were assessed. Comparing with control group mean serum Cu and Crl concentrations were significantly increased. We suspect that antiepileptic drugs may influence the serum Cu and Crl concentrations by hepatic enzymes induction. Clinical picture of epilepsy and treatment duration does not influence serum Cu and Crl concentrations.
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