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The method of calculating the threshold levels of blood plasma cholesterol and triglycerids was analysed. The threshold levels were used for a genetic analysis of the relatives of the probands with coronary heart disease combined with hyperlipoproteinemia. Among 25 relatives of probands suffering coronary heart disease combined with hyperlipoproteinemia the latter was found in 15, while among 25 relatives of probands suffering coronary heart disease and having normal lipid levels hyperlipoproteinemia was found only in 2. The presented data characterise the peculiarities of the diagnosis of familial (primary) hyperlipoproteinemia and support the importance of the hereditary factor in the regulation of lipid metabolsm in the families of coronary atherosclerosis patients.
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