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A case is reported by the authors of a progressive benzene hemopathy with a final leukemic evolution. The leukemic pattern was an autopsy ""surprise'', inasmuch as never, even in the hours just before death, could leukemic cells be detected in the blood stream. The authors discuss some pathogenic aspects, with particular emphasis on the systemic spreading of a malignant hemopathy from very few leukemic cells in bone marrow.
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