Biomaterial Database

[The coagulating and fibrinolytic activities of the blood in smokers]. 1998

A K German

A total of 110 essentially healthy male subjects 23 to 32 years old, with 80 of these smoking tobacco (cigarettes) were studied for the condition of coagulative and fibrinolytic activity with the aid of thromboelastograph and coagulograph. Measured in the venous blood plasma was concentration of fibrinogen. Also studied in the above male population were such parameters as completion of clot formation, time of reaction, time of coagulation, maximal elasticity of the clot, thromboelastographic index, maximum amplitude, and amplitude 10 minutes of the commencement of retraction and fibrinolysis, percentage of fibrinolysis. Smoking tobacco has been found out to make for enhancement of blood coagulative and fibrinolytic activities, particularly in persons with a more that 10-year history of smoking.

UI	MeSH Term	Description	Entries
D008297	Male		Males
D001777	Blood Coagulation	The process of the interaction of BLOOD COAGULATION FACTORS that results in an insoluble FIBRIN clot.	Blood Clotting,Coagulation, Blood,Blood Clottings,Clotting, Blood
D005340	Fibrinogen	Plasma glycoprotein clotted by thrombin, composed of a dimer of three non-identical pairs of polypeptide chains (alpha, beta, gamma) held together by disulfide bonds. Fibrinogen clotting is a sol-gel change involving complex molecular arrangements: whereas fibrinogen is cleaved by thrombin to form polypeptides A and B, the proteolytic action of other enzymes yields different fibrinogen degradation products.	Coagulation Factor I,Factor I,Blood Coagulation Factor I,gamma-Fibrinogen,Factor I, Coagulation,gamma Fibrinogen
D005342	Fibrinolysis	The natural enzymatic dissolution of FIBRIN.	Fibrinolyses
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults
D000704	Analysis of Variance	A statistical technique that isolates and assesses the contributions of categorical independent variables to variation in the mean of a continuous dependent variable.	ANOVA,Analysis, Variance,Variance Analysis,Analyses, Variance,Variance Analyses
D012907	Smoking	Willful or deliberate act of inhaling and exhaling SMOKE from burning substances or agents held by hand.	Smoking Behaviors,Smoking Habit,Behavior, Smoking,Behaviors, Smoking,Habit, Smoking,Habits, Smoking,Smoking Behavior,Smoking Habits
D013916	Thrombelastography	Use of a thrombelastograph, which provides a continuous graphic record of the physical shape of a clot during fibrin formation and subsequent lysis.	Thromboelastography,Thromboelastometry
D013997	Time Factors	Elements of limited time intervals, contributing to particular results or situations.	Time Series,Factor, Time,Time Factor