Biomaterial Database

[Clinical research on a new corticoid-containing topical drug]. 1976

H C Sturde

In the present paper, the clinical trial of a new difluorinated corticosteroid suitable for topical use is reported. Because of its proven efficacy in very different dermatoses, it is useful as a new reliable product for external use having a broad spectrum of indications. Altogether, 50 patients were treated for a number of dermatoses (various forms of eczema, neurodermitis constitutionalis among other rare skin diseases). Complications, especially skin lesions due to corticosteroids, were not observed. The availability of the test preparation in three different forms has the advantage that it is not only suitable for the primary dermatosis, but it can also be adapted to the various degrees of acuteness.

UI	MeSH Term	Description	Entries
D009824	Ointments	Semisolid preparations used topically for protective emollient effects or as a vehicle for local administration of medications. Ointment bases are various mixtures of fats, waxes, animal and plant oils and solid and liquid hydrocarbons.	Ointment,Paste,Pastes,Salve,Unguent,Salves,Skin Ointment,Unguents,Ointment, Skin
D011244	Pregnadienediols	Doubly unsaturated pregnane derivatives with two hydroxy groups substituted anywhere on the rings or side chains.	Dihydroxypregnadienes
D005448	Fluocortolone	A glucocorticoid with anti-inflammatory activity used topically for various skin disorders.	Fluocortolone Caproate,Fluocortolone Pivalate,Ultralan,Caproate, Fluocortolone,Pivalate, Fluocortolone
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000287	Administration, Topical	The application of drug preparations to the surfaces of the body, especially the skin (ADMINISTRATION, CUTANEOUS) or mucous membranes. This method of treatment is used to avoid systemic side effects when high doses are required at a localized area or as an alternative systemic administration route, to avoid hepatic processing for example.	Drug Administration, Topical,Administration, Topical Drug,Topical Administration,Topical Drug Administration,Administrations, Topical,Administrations, Topical Drug,Drug Administrations, Topical,Topical Administrations,Topical Drug Administrations
D012871	Skin Diseases	Diseases involving the DERMIS or EPIDERMIS.	Dermatoses,Skin and Subcutaneous Tissue Disorders,Dermatosis,Skin Disease