Biomaterial Database

Influence of feed restriction in primiparous lactating sows on body condition and metabolic parameters. 1998

H Quesnel, and A Pasquier, and A M Mounier, and I Louveau, and A Prunier

Station de recherches porcines, Inra, Saint-Gilles, France. quesnel@st-gilles.rennes.inra.fr

Twenty-four primiparous sows were allocated at farrowing to a high (H: 5.5-6 kg feed/day) or a low (L: 2.5-3 kg/day) level of feeding. Litters (8-10 piglets) were weaned at 28+/-2 days. Serial blood samples were collected 1 day before weaning (W-1), in the hours following weaning (W) and 1 day after (W + 1). L sows lost significantly more weight (38 versus 15 kg) and backfat (5.3 versus 2.3 mm) during lactation than H sows. On day W-1, L sows had higher mean concentrations of NEFA (P < 0.01) and GH (P < 0.1 ) and lower concentrations of insulin and IGF-I (P < 0.05) than H sows. Mean concentrations of glucose and cortisol did not differ between groups of sows. On day W + 1, these parameters were not different between treatments, except IGF-I concentrations which remained lower in L than in H sows (P < 0.05). We conclude that lactating primiparous sows alter secretion of metabolic hormones to favour mobilization of body reserves to support milk production. Low insulin and IGF-I may be involved in reduced ovarian activity at and after weaning, through LH-dependent and independent pathways.

UI	MeSH Term	Description	Entries
D007334	Insulin-Like Growth Factor I	A well-characterized basic peptide believed to be secreted by the liver and to circulate in the blood. It has growth-regulating, insulin-like, and mitogenic activities. This growth factor has a major, but not absolute, dependence on GROWTH HORMONE. It is believed to be mainly active in adults in contrast to INSULIN-LIKE GROWTH FACTOR II, which is a major fetal growth factor.	IGF-I,Somatomedin C,IGF-1,IGF-I-SmC,Insulin Like Growth Factor I,Insulin-Like Somatomedin Peptide I,Insulin Like Somatomedin Peptide I
D007774	Lactation	The processes of milk secretion by the maternal MAMMARY GLANDS after PARTURITION. The proliferation of the mammary glandular tissue, milk synthesis, and milk expulsion or let down are regulated by the interactions of several hormones including ESTRADIOL; PROGESTERONE; PROLACTIN; and OXYTOCIN.	Lactation, Prolonged,Milk Secretion,Lactations, Prolonged,Milk Secretions,Prolonged Lactation,Prolonged Lactations
D008098	Litter Size	The number of offspring produced at one birth by a viviparous animal.	Litter Sizes,Size, Litter,Sizes, Litter
D010298	Parity	The number of offspring a female has borne. It is contrasted with GRAVIDITY, which refers to the number of pregnancies, regardless of outcome.	Multiparity,Nulliparity,Primiparity,Parity Progression Ratio,Parity Progression Ratios,Ratio, Parity Progression,Ratios, Parity Progression
D001823	Body Composition	The relative amounts of various components in the body, such as percentage of body fat.	Body Compositions,Composition, Body,Compositions, Body
D005230	Fatty Acids, Nonesterified	FATTY ACIDS found in the plasma that are complexed with SERUM ALBUMIN for transport. These fatty acids are not in glycerol ester form.	Fatty Acids, Free,Free Fatty Acid,Free Fatty Acids,NEFA,Acid, Free Fatty,Acids, Free Fatty,Acids, Nonesterified Fatty,Fatty Acid, Free,Nonesterified Fatty Acids
D005260	Female		Females
D005508	Food Deprivation	The withholding of food in a structured experimental situation.	Deprivation, Food,Deprivations, Food,Food Deprivations
D000818	Animals	Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA.	Animal,Metazoa,Animalia
D013006	Growth Hormone	A polypeptide that is secreted by the adenohypophysis (PITUITARY GLAND, ANTERIOR). Growth hormone, also known as somatotropin, stimulates mitosis, cell differentiation and cell growth. Species-specific growth hormones have been synthesized.	Growth Hormone, Recombinant,Pituitary Growth Hormone,Recombinant Growth Hormone,Somatotropin,Somatotropin, Recombinant,Growth Hormone, Pituitary,Growth Hormones Pituitary, Recombinant,Pituitary Growth Hormones, Recombinant,Recombinant Growth Hormones,Recombinant Pituitary Growth Hormones,Recombinant Somatotropins,Somatotropins, Recombinant,Growth Hormones, Recombinant,Recombinant Somatotropin