Metastatic testicular Sertoli-cell tumor: cytopathologic findings on fine-needle aspiration. 1998

J D Kronz, and T L Nicol, and D L Rosenthal, and S Z Ali
Johns K. Frost Cytopathology Laboratory, Department of Pathology, Johns Hopkins Hospital, Baltimore, Maryland 21287-6940, USA.

Malignant Sertoli-cell tumors of the testis are exceedingly rare. We present cytopathologic findings in pelvic metastasis of such a tumor in a 45-year-old man, diagnosed on fine-needle aspiration, 2 months after radical orchiectomy. Ultrasound-guided aspirate showed tissue fragments and isolated discohesive tumor cells with characteristics of testicular Sertoli cells. Immunoperoxidase (IPOX) studies and histopathologic correlation with the primary testicular tumor are also presented. Cytopathologic features complimented by IPOX studies should allow an accurate diagnosis of this rare entity, when seen at metastatic sites.

UI MeSH Term Description Entries
D008297 Male Males
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D001707 Biopsy, Needle Removal and examination of tissue obtained through a transdermal needle inserted into the specific region, organ, or tissue being analyzed. Aspiration Biopsy,Puncture Biopsy,Aspiration Biopsies,Biopsies, Aspiration,Biopsies, Needle,Biopsies, Puncture,Biopsy, Aspiration,Biopsy, Puncture,Needle Biopsies,Needle Biopsy,Puncture Biopsies
D012707 Sertoli Cell Tumor Gonadal neoplasm composed entirely of SERTOLI CELLS or may have a component of GRANULOSA CELLS. Some of the Sertoli cell tumors produce ESTROGEN or ANDROGENS, but seldom in sufficient quantity to cause clinical symptoms such as FEMINIZATION or masculinization (VIRILISM). Tumor, Sertoli Cell
D013736 Testicular Neoplasms Tumors or cancer of the TESTIS. Germ cell tumors (GERMINOMA) of the testis constitute 95% of all testicular neoplasms. Cancer of Testis,Cancer of the Testes,Testicular Cancer,Testicular Neoplasm,Testicular Tumor,Testis Cancer,Cancer of the Testis,Neoplasms, Testicular,Neoplasms, Testis,Testicular Tumors,Testis Neoplasms,Tumor of Rete Testis,Cancer, Testicular,Cancer, Testis,Cancers, Testicular,Cancers, Testis,Neoplasm, Testicular,Neoplasm, Testis,Rete Testis Tumor,Rete Testis Tumors,Testicular Cancers,Testis Cancers,Testis Neoplasm,Testis Tumor, Rete,Testis Tumors, Rete,Tumor, Testicular,Tumors, Testicular
D015898 Tomography Scanners, X-Ray Computed X-ray image-detecting devices that make a focused image of body structures lying in a predetermined plane from which more complex images are computed. CAT Scanners, X-Ray,CT Scanner, X-Ray,Computed Tomography Scanners, X-Ray,Tomography, Computed, Scanners,Tomography, X-Ray Computed, Scanners,CAT Scanner, X-Ray,Computed Tomography Scanner, X-Ray,Tomography, X-Ray Computed, Scanner,X-Ray Computed Tomography Scanner,X-Ray Computed Tomography Scanners,CAT Scanner, X Ray,CAT Scanners, X Ray,CT Scanner, X Ray,CT Scanners, X-Ray,Computed Tomography Scanner, X Ray,Computed Tomography Scanners, X Ray,Scanner, X-Ray CAT,Scanner, X-Ray CT,Scanners, X-Ray CAT,Scanners, X-Ray CT,Tomography Scanners, X Ray Computed,X Ray Computed Tomography Scanner,X Ray Computed Tomography Scanners,X-Ray CAT Scanner,X-Ray CAT Scanners,X-Ray CT Scanner,X-Ray CT Scanners

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