Biomaterial Database

Adjuvant radiotherapy in the treatment of breast cancer. 1998

C F Hess, and H Schmidberger

Klinik fur Strahlentherapie und Radioonkologie, Göttingen, Germany.

Recent studies on the impact of adjuvant radiotherapy on local control, survival and quality of life in patients with breast cancer have been evaluated. Following these studies, breast conserving surgery with subsequent radiation therapy is the standard treatment for early breast cancer. In advanced disease, radiation is indicated for patients with T3- or T4 and/or with four or more positive lymph nodes. In general, radiotherapy leads to a 2-4 fold reduction of local relapse. In addition, there is considerable evidence that radiotherapy is associated with a higher overall survival. In elderly women postoperative radiotherapy should not be withheld. An extensive intraductal component (EIC) or multicentric disease can be compatible with breast conserving therapy if surgery has been completed. Self assessment of patients rated the cosmetic results of breast conserving therapy higher than mastectomy and breast reconstruction.

UI	MeSH Term	Description	Entries
D001943	Breast Neoplasms	Tumors or cancer of the human BREAST.	Breast Cancer,Breast Tumors,Cancer of Breast,Breast Carcinoma,Cancer of the Breast,Human Mammary Carcinoma,Malignant Neoplasm of Breast,Malignant Tumor of Breast,Mammary Cancer,Mammary Carcinoma, Human,Mammary Neoplasm, Human,Mammary Neoplasms, Human,Neoplasms, Breast,Tumors, Breast,Breast Carcinomas,Breast Malignant Neoplasm,Breast Malignant Neoplasms,Breast Malignant Tumor,Breast Malignant Tumors,Breast Neoplasm,Breast Tumor,Cancer, Breast,Cancer, Mammary,Cancers, Mammary,Carcinoma, Breast,Carcinoma, Human Mammary,Carcinomas, Breast,Carcinomas, Human Mammary,Human Mammary Carcinomas,Human Mammary Neoplasm,Human Mammary Neoplasms,Mammary Cancers,Mammary Carcinomas, Human,Neoplasm, Breast,Neoplasm, Human Mammary,Neoplasms, Human Mammary,Tumor, Breast
D003131	Combined Modality Therapy	The treatment of a disease or condition by several different means simultaneously or sequentially. Chemoimmunotherapy, RADIOIMMUNOTHERAPY, chemoradiotherapy, cryochemotherapy, and SALVAGE THERAPY are seen most frequently, but their combinations with each other and surgery are also used.	Multimodal Treatment,Therapy, Combined Modality,Combined Modality Therapies,Modality Therapies, Combined,Modality Therapy, Combined,Multimodal Treatments,Therapies, Combined Modality,Treatment, Multimodal,Treatments, Multimodal
D005260	Female		Females
D005500	Follow-Up Studies	Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease.	Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D018714	Radiotherapy, Adjuvant	Radiotherapy given to augment some other form of treatment such as surgery or chemotherapy. Adjuvant radiotherapy is commonly used in the therapy of cancer and can be administered before or after the primary treatment.	Adjuvant Radiotherapy,Adjuvant Radiotherapies,Radiotherapies, Adjuvant