Pathomorphology of lungs and heart in experimental prolonged hypoxia. 1976

M Konopiński, and L Zimnoch

The authors carried out morphological examinations of lungs and heart in 20 days with prolonged hypoxia caused by surgical subglottic stenosis of the trachea by 50%. The studies showed that 30 and 60 days after the onset of hypoxia changes such as emphysema and chronic bronchitis developed in the lungs showing an increasing tendency, while in the myocardium microgranular disintegration and fatty infiltration of muscle fibres with simultaneous disappearance of glycogen was seen in the first period-after 30 days - while later, after 60 days fibrosis developed.

UI MeSH Term Description Entries
D008168 Lung Either of the pair of organs occupying the cavity of the thorax that effect the aeration of the blood. Lungs
D008297 Male Males
D009206 Myocardium The muscle tissue of the HEART. It is composed of striated, involuntary muscle cells (MYOCYTES, CARDIAC) connected to form the contractile pump to generate blood flow. Muscle, Cardiac,Muscle, Heart,Cardiac Muscle,Myocardia,Cardiac Muscles,Heart Muscle,Heart Muscles,Muscles, Cardiac,Muscles, Heart
D004285 Dogs The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065) Canis familiaris,Dog
D004699 Endocardium The innermost layer of the heart, comprised of endothelial cells. Endocardiums
D005260 Female Females
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D000860 Hypoxia Sub-optimal OXYGEN levels in the ambient air of living organisms. Anoxia,Oxygen Deficiency,Anoxemia,Deficiency, Oxygen,Hypoxemia,Deficiencies, Oxygen,Oxygen Deficiencies
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor
D014135 Tracheal Stenosis A pathological narrowing of the TRACHEA. Stenoses, Tracheal,Stenosis, Tracheal,Tracheal Stenoses

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