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To assess the efficacy of ammoniation in the detoxification of endophyte-infected tall fescue (Festuca arundinacea Schreb), 40 male Harlan Sprague-Dawley rats were randomly assigned to the following four treatments for 28 d: endophyte-free (E-), endophyte-infected (E+), ammoniated (2% dry matter basis, 7 d) endophyte-free (AE-), and ammoniated endophyte-infected (AE+) tall fescue seed. Total pyrrolizidine alkaloid (N-acetyl and N-formyl loline) and ergovaline contents of endophyte-infected fescue seed were reduced 24 and 54%, respectively, by ammoniation. Endophyte-infected treatment groups had lower (P < 0.01) daily feed intakes (DFI), daily weight gains (DWG), feed efficiencies, and primary serum hemagglutination titers to sheep red blood cell (SRBC) immunization than endophyte-free treatment groups. Performance parameters were higher (P < 0.01) for ammoniated diets in comparison to non-ammoniated diets; however, anti-SRBC titers were not significantly different. When compared to the E+ diet, the AE+ diet increased (P < 0.01) DFI (24%), DWG (41%) and feed efficiency (13%).
A Simeone, and
M L Westendorf, and
R E Tucker, and
L P Bush, and
G E Mitchell
August 1998,
Drug and chemical toxicology,
A Simeone, and
M L Westendorf, and
R E Tucker, and
L P Bush, and
G E Mitchell
February 1998,
Drug and chemical toxicology,
A Simeone, and
M L Westendorf, and
R E Tucker, and
L P Bush, and
G E Mitchell
January 1988,
Theriogenology,
A Simeone, and
M L Westendorf, and
R E Tucker, and
L P Bush, and
G E Mitchell
January 1987,
Drug and chemical toxicology,
A Simeone, and
M L Westendorf, and
R E Tucker, and
L P Bush, and
G E Mitchell
June 1989,
Drug and chemical toxicology,
A Simeone, and
M L Westendorf, and
R E Tucker, and
L P Bush, and
G E Mitchell
May 1984,
Journal of animal science,
A Simeone, and
M L Westendorf, and
R E Tucker, and
L P Bush, and
G E Mitchell
January 1993,
Drug and chemical toxicology,
A Simeone, and
M L Westendorf, and
R E Tucker, and
L P Bush, and
G E Mitchell
January 1996,
Drug and chemical toxicology,
A Simeone, and
M L Westendorf, and
R E Tucker, and
L P Bush, and
G E Mitchell
January 1987,
Comparative biochemistry and physiology. C, Comparative pharmacology and toxicology,
A Simeone, and
M L Westendorf, and
R E Tucker, and
L P Bush, and
G E Mitchell
September 1988,
Theriogenology,
