-transparent.png){kind=logo}
This prospective study involves 644 patients who received ossification prophylaxis by means of the drug diclofenac after implantation (87.5%) or revision (12.5%) of a total hip endoprosthesis between August 1992 and June 1994. One hundred patients (15.5%) stopped the treatment because of side-effects of the drug, and medication was stopped when gastrointestinal troubles occurred. The follow-up examination after 6 months revealed ossification of HO degree 1 according to Brooker in 13.8% of cases, of degree 2 in 4.8%, and of degree 3 in 1.4% of cases. Severe HO of degree 4 was not observed at all, and 80% of the patients exhibited no ossification what ever. Thus, in comparison to our own studies and to the literature, diclofenac must be regarded as an extremely effective drug for the prevention of ossification.
M Jockheck, and
R Willms, and
R Volkmann, and
S Sell, and
S Weller, and
W Küsswetter
October 1996,
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al],
M Jockheck, and
R Willms, and
R Volkmann, and
S Sell, and
S Weller, and
W Küsswetter
January 1997,
Chirurgia narzadow ruchu i ortopedia polska,
M Jockheck, and
R Willms, and
R Volkmann, and
S Sell, and
S Weller, and
W Küsswetter
February 1992,
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al],
M Jockheck, and
R Willms, and
R Volkmann, and
S Sell, and
S Weller, and
W Küsswetter
January 1988,
Revue de chirurgie orthopedique et reparatrice de l'appareil moteur,
M Jockheck, and
R Willms, and
R Volkmann, and
S Sell, and
S Weller, and
W Küsswetter
January 1979,
Duodecim; laaketieteellinen aikakauskirja,
M Jockheck, and
R Willms, and
R Volkmann, and
S Sell, and
S Weller, and
W Küsswetter
February 1994,
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology,
M Jockheck, and
R Willms, and
R Volkmann, and
S Sell, and
S Weller, and
W Küsswetter
August 2003,
Pharmacy world & science : PWS,
M Jockheck, and
R Willms, and
R Volkmann, and
S Sell, and
S Weller, and
W Küsswetter
January 1994,
Journal of back and musculoskeletal rehabilitation,
M Jockheck, and
R Willms, and
R Volkmann, and
S Sell, and
S Weller, and
W Küsswetter
July 1990,
Orthopaedic review,
M Jockheck, and
R Willms, and
R Volkmann, and
S Sell, and
S Weller, and
W Küsswetter
November 1994,
Der Chirurg; Zeitschrift fur alle Gebiete der operativen Medizen,
