Achalasia in a sixty-four-year-old man. 1998

E A Komisaruk, and N E Seymour
Yale-New Haven Hospital, Connecticut, USA. komisaea@biomed.med.yale.edu

Achalasia is an esophageal motility disorder characterized by increased lower esophageal sphincter pressure and absence of peristalsis in the lower esophagus. Patients typically present with complaints of progressive difficulty swallowing over a period of several years. Diagnosis is confirmed by esophageal manometry. Complications of achalasia include esophagitis, aspiration and possibly an increased risk of esophageal carcinoma. Medical treatment options include pneumatic dilatation, esophageal bougienage, nitrates, calcium channel blockers and botulinum toxin injections. The primary method of surgical treatment is the Heller myotomy, in which longitudinal incisions are made in the muscle fibers of the lower esophageal sphincter to reduce sphincter pressure. Frequently, a fundoplication is performed in addition to the myotomy to decrease the likelihood of development of gastroesophageal reflux. In recent years, the Heller myotomy has been performed both thoracoscopically and laparoscopically. An additional development has been the placement of an endoscope in the esophagus to provide transillumination during surgery; intraoperative endoscopy allows improved assessment of the depth of myotomy incisions and reduces the risk of esophageal perforation. The case report below describes a 64-year-old-man with achalasia who presented with persistent dysphagia despite multiple attempts at medical treatment. A laparoscopic Heller myotomy with Toupet fundoplication was performed with subsequent eradication of symptoms. A discussion of the epidemiology, etiology, clinical presentation, diagnosis and treatment of achalasia follows the case report.

UI MeSH Term Description Entries
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D010535 Laparoscopy A procedure in which a laparoscope (LAPAROSCOPES) is inserted through a small incision near the navel to examine the abdominal and pelvic organs in the PERITONEAL CAVITY. If appropriate, biopsy or surgery can be performed during laparoscopy. Celioscopy,Laparoscopic Surgical Procedures,Peritoneoscopy,Surgical Procedures, Laparoscopic,Laparoscopic Assisted Surgery,Laparoscopic Surgery,Laparoscopic Surgical Procedure,Procedure, Laparoscopic Surgical,Procedures, Laparoscopic Surgical,Surgery, Laparoscopic,Surgical Procedure, Laparoscopic,Celioscopies,Laparoscopic Assisted Surgeries,Laparoscopic Surgeries,Laparoscopies,Peritoneoscopies,Surgeries, Laparoscopic,Surgeries, Laparoscopic Assisted,Surgery, Laparoscopic Assisted
D004106 Dilatation The act of dilating. Dilation,Dilatations,Dilations
D004931 Esophageal Achalasia A motility disorder of the ESOPHAGUS in which the LOWER ESOPHAGEAL SPHINCTER (near the CARDIA) fails to relax resulting in functional obstruction of the esophagus, and DYSPHAGIA. Achalasia is characterized by a grossly contorted and dilated esophagus (megaesophagus). Achalasia, Esophageal,Cardiospasm,Megaesophagus,Achalasia,Achalasias,Achalasias, Esophageal,Cardiospasms,Esophageal Achalasias
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man

Related Publications

E A Komisaruk, and N E Seymour
May 2019, BMJ case reports,
E A Komisaruk, and N E Seymour
January 2010, Eksperimental'naia i klinicheskaia gastroenterologiia = Experimental & clinical gastroenterology,
E A Komisaruk, and N E Seymour
September 1954, Gan,
E A Komisaruk, and N E Seymour
February 1965, New York state journal of medicine,
E A Komisaruk, and N E Seymour
July 1971, South Dakota journal of medicine,
E A Komisaruk, and N E Seymour
September 1967, The American journal of medicine,
E A Komisaruk, and N E Seymour
January 2010, The Canadian journal of clinical pharmacology = Journal canadien de pharmacologie clinique,
E A Komisaruk, and N E Seymour
February 2018, Presse medicale (Paris, France : 1983),
E A Komisaruk, and N E Seymour
September 1970, South Dakota journal of medicine,
E A Komisaruk, and N E Seymour
March 1987, The Journal of bone and joint surgery. American volume,
Copied contents to your clipboard!