Coagulation factor V Leiden mutation was detected in the patients with activated protein C resistance in Thailand.
1998
P Arnutti, and
M Hiyoshi, and
W Prayoonwiwat, and
O Nathalang, and
C Suwanasophon, and
R Kokaseam, and
N Tatsumi
UI
MeSH Term
Description
Entries
D009154
Mutation
Any detectable and heritable change in the genetic material that causes a change in the GENOTYPE and which is transmitted to daughter cells and to succeeding generations.
Mutations
D005165
Factor V
Heat- and storage-labile plasma glycoprotein which accelerates the conversion of prothrombin to thrombin in blood coagulation. Factor V accomplishes this by forming a complex with factor Xa, phospholipid, and calcium (prothrombinase complex). Deficiency of factor V leads to Owren's disease.
Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D013785
Thailand
Formerly known as Siam, this is a Southeast Asian nation at the center of the Indochina peninsula. Bangkok is the capital city.
Kingdom of Thailand,Siam
D015995
Prevalence
The total number of cases of a given disease in a specified population at a designated time. It is differentiated from INCIDENCE, which refers to the number of new cases in the population at a given time.
Period Prevalence,Point Prevalence,Period Prevalences,Point Prevalences,Prevalence, Period,Prevalence, Point,Prevalences
D020016
Activated Protein C Resistance
A hemostatic disorder characterized by a poor anticoagulant response to activated protein C (APC). The activated form of Factor V (Factor Va) is more slowly degraded by activated protein C. Factor V Leiden mutation (R506Q) is the most common cause of APC resistance.
APC Resistance,Resistance, APC
Related Publications
P Arnutti, and
M Hiyoshi, and
W Prayoonwiwat, and
O Nathalang, and
C Suwanasophon, and
R Kokaseam, and
N Tatsumi