BIOMAT Database Logo BIOMAT Database Logo

Elevated adhesiveness/aggregation of peripheral blood leukocytes in patients with major depression. 1998

Z Zemishlany, and D Aizenberg, and C Klein, and I Modai, and M Aronson, and A Weizman
Geha Psychiatric Hospital, Rabin Medical Center, Petah Tikva, Sackler Faculty of Medicine, Tel Aviv University, Israel.

A simple slide test was used to determine the effects of major depression (MD) and heterocyclic antidepressants on leukocyte adhesiveness/aggregation (LAA) in the peripheral blood. Eighty subjects were categorized into four equal groups: untreated-MD patients, treated-MD patients, nondepressed patients treated with antidepressants and healthy controls. Significantly higher LAA values were observed both in untreated- and treated-MD patients, 13.8+/-1.7% and 13.5+/-1.9% respectively, compared to nondepressed-treated patients and healthy controls, 5.4+/-0.9% and 6.4+/-0.7% respectively (P < 0.0001). Increased LAA was associated with the depressive episode, was not affected by antidepressants and may potentially serve as a useful laboratory state marker for MD.

UI MeSH Term Description Entries
D007962 Leukocytes White blood cells. These include granular leukocytes (BASOPHILS; EOSINOPHILS; and NEUTROPHILS) as well as non-granular leukocytes (LYMPHOCYTES and MONOCYTES). Blood Cells, White,Blood Corpuscles, White,White Blood Cells,White Blood Corpuscles,Blood Cell, White,Blood Corpuscle, White,Corpuscle, White Blood,Corpuscles, White Blood,Leukocyte,White Blood Cell,White Blood Corpuscle
D008297 Male Males
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D002448 Cell Adhesion Adherence of cells to surfaces or to other cells. Adhesion, Cell,Adhesions, Cell,Cell Adhesions
D002449 Cell Aggregation The phenomenon by which dissociated cells intermixed in vitro tend to group themselves with cells of their own type. Aggregation, Cell,Aggregations, Cell,Cell Aggregations
D003866 Depressive Disorder An affective disorder manifested by either a dysphoric mood or loss of interest or pleasure in usual activities. The mood disturbance is prominent and relatively persistent. Depression, Endogenous,Depression, Neurotic,Depression, Unipolar,Depressive Syndrome,Melancholia,Neurosis, Depressive,Unipolar Depression,Depressions, Endogenous,Depressions, Neurotic,Depressions, Unipolar,Depressive Disorders,Depressive Neuroses,Depressive Neurosis,Depressive Syndromes,Disorder, Depressive,Disorders, Depressive,Endogenous Depression,Endogenous Depressions,Melancholias,Neuroses, Depressive,Neurotic Depression,Neurotic Depressions,Syndrome, Depressive,Syndromes, Depressive,Unipolar Depressions
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults
D000928 Antidepressive Agents Mood-stimulating drugs used primarily in the treatment of affective disorders and related conditions. Several MONOAMINE OXIDASE INHIBITORS are useful as antidepressants apparently as a long-term consequence of their modulation of catecholamine levels. The tricyclic compounds useful as antidepressive agents (ANTIDEPRESSIVE AGENTS, TRICYCLIC) also appear to act through brain catecholamine systems. A third group (ANTIDEPRESSIVE AGENTS, SECOND-GENERATION) is a diverse group of drugs including some that act specifically on serotonergic systems. Antidepressant,Antidepressant Drug,Antidepressant Medication,Antidepressants,Antidepressive Agent,Thymoanaleptic,Thymoanaleptics,Thymoleptic,Thymoleptics,Antidepressant Drugs,Agent, Antidepressive,Drug, Antidepressant,Medication, Antidepressant

Related Publications

Z Zemishlany, and D Aizenberg, and C Klein, and I Modai, and M Aronson, and A Weizman
Phagocytosis and adhesiveness of peripheral blood polymorphonuclear leukocytes in patients with rapidly progressive periodontitis.
November 1991, Journal of oral pathology & medicine : official publication of the International Association of Oral Pathologists and the American Academy of Oral Pathology,
Z Zemishlany, and D Aizenberg, and C Klein, and I Modai, and M Aronson, and A Weizman
The erythrocyte adhesiveness/aggregation test in the peripheral blood of patients with ischemic brain events.
May 2001, Acta neurologica Scandinavica,
Z Zemishlany, and D Aizenberg, and C Klein, and I Modai, and M Aronson, and A Weizman
The state of leukocyte adhesiveness/aggregation in the peripheral blood of patients with respiratory tract infections.
January 1990, Respiration; international review of thoracic diseases,
Z Zemishlany, and D Aizenberg, and C Klein, and I Modai, and M Aronson, and A Weizman
State of leukocyte adhesiveness/aggregation in the peripheral blood of pemphigus and psoriatic patients.
January 1990, Archives of dermatological research,
Z Zemishlany, and D Aizenberg, and C Klein, and I Modai, and M Aronson, and A Weizman
[Adhesiveness of peripheral blood neutrophils in patients with asthma].
July 1974, Polski tygodnik lekarski (Warsaw, Poland : 1960),
Z Zemishlany, and D Aizenberg, and C Klein, and I Modai, and M Aronson, and A Weizman
Accelerated apoptosis of blood leukocytes and oxidative stress in blood of patients with major depression.
April 2008, Progress in neuro-psychopharmacology & biological psychiatry,
Z Zemishlany, and D Aizenberg, and C Klein, and I Modai, and M Aronson, and A Weizman
Increased erythrocyte adhesiveness and aggregation in peripheral venous blood of women with pregnancy-induced hypertension.
August 2001, Obstetrics and gynecology,
Z Zemishlany, and D Aizenberg, and C Klein, and I Modai, and M Aronson, and A Weizman
[Adhesiveness and aggregation of blood platelets].
September 1968, Saishin igaku. Modern medicine,
Z Zemishlany, and D Aizenberg, and C Klein, and I Modai, and M Aronson, and A Weizman
Increased erythrocyte adhesiveness/aggregation in the peripheral venous blood of patients with ischaemic heart disease and an eventful course.
April 2001, Acta cardiologica,
Z Zemishlany, and D Aizenberg, and C Klein, and I Modai, and M Aronson, and A Weizman
Blood coagulation and platelet aggregation in major depression.
September 1996, Journal of affective disorders,
Copied contents to your clipboard!