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Dopamine Beta Hydroxylase (DBH) activity was determined in 24 deeply comatose patients enrolled in the Collaborative Study of Cerebral Survival. All patients had been without cerebral responsiveness or spontaneous respirations for at least 15 minutes. Patients were examined, EEGs performed and blood for DBH drawn within 24 hours of the cerebral insult. DBH activity was lower in the deeply comatose patients than in a group of 51 age matched normal individuals. It is postulated that destruction or inactivation of the central nervous system (CNS) and particularly of the cerebrum may result in lowered serum DBH activity through decreased activation of sympathetic nerve terminals.
A N Lieberman, and
J Korein, and
L Freedman, and
K Siegel
March 1971,
Circulation research,
A N Lieberman, and
J Korein, and
L Freedman, and
K Siegel
January 1975,
Psychosomatic medicine,
A N Lieberman, and
J Korein, and
L Freedman, and
K Siegel
January 1978,
Biochemical pharmacology,
A N Lieberman, and
J Korein, and
L Freedman, and
K Siegel
September 1976,
Archives of neurology,
A N Lieberman, and
J Korein, and
L Freedman, and
K Siegel
May 1972,
The New England journal of medicine,
A N Lieberman, and
J Korein, and
L Freedman, and
K Siegel
October 1980,
Biological psychiatry,
A N Lieberman, and
J Korein, and
L Freedman, and
K Siegel
December 1976,
Clinical science and molecular medicine. Supplement,
A N Lieberman, and
J Korein, and
L Freedman, and
K Siegel
January 1977,
Clinical and experimental pharmacology & physiology,
A N Lieberman, and
J Korein, and
L Freedman, and
K Siegel
January 1979,
Stroke,
A N Lieberman, and
J Korein, and
L Freedman, and
K Siegel
April 1985,
Journal of neurology, neurosurgery, and psychiatry,
