Comparative efficacy of pyrethrum marc with albendazole against sheep gastrointestinal nematodes. 1998

J M Mbaria, and T E Maitho, and E S Mitema, and D J Muchiri
University of Nairobi, Faculty of Veterinary Medicine, Department of Public Health, Pharmacology and Toxicology, Kenya.

The efficacies of pyrethrum marc and of albendazole against experimental sheep gastrointestinal nematode infection were compared. Sheep was infected orally with 10,000 larvae (Haemonchus spp. (60.1%), Oesophagostomum spp. (13.9%), Trichostrongylus spp. (13.2%), Cooperia spp. (8.3%), Nematodirus spp. (3.5%), Strongyloides spp. (0.8%) and Ostertagia spp. (0.2%). Faecal egg count reduction in albendazole-treated sheep was 100% by day 4 following treatment, compared to 37.03%, 31.3%, 38.9% and 51.8% on days 4, 6, 8 and 10 in pyrethrum mare-treated sheep. These reductions were statistically significant on days 8 and 10 post-treatment (p < 0.05). The potential for using pyrethrins for helminth treatment is discussed.

UI MeSH Term Description Entries
D007411 Intestinal Diseases, Parasitic Infections of the INTESTINES with PARASITES, commonly involving PARASITIC WORMS. Infections with roundworms (NEMATODE INFECTIONS) and tapeworms (CESTODE INFECTIONS) are also known as HELMINTHIASIS. Parasitic Intestinal Diseases,Disease, Parasitic Intestinal,Diseases, Parasitic Intestinal,Intestinal Disease, Parasitic,Parasitic Intestinal Disease
D008297 Male Males
D008517 Phytotherapy Use of plants or herbs to treat diseases or to alleviate pain. Herb Therapy,Herbal Therapy
D009349 Nematode Infections Infections by nematodes, general or unspecified. Infections, Nematode,Infection, Nematode,Nematode Infection
D010270 Parasite Egg Count Determination of parasite eggs in feces. Count, Parasite Egg,Counts, Parasite Egg,Egg Count, Parasite,Egg Counts, Parasite,Parasite Egg Counts
D010936 Plant Extracts Concentrated pharmaceutical preparations of plants obtained by removing active constituents with a suitable solvent, which is evaporated away, and adjusting the residue to a prescribed standard. Herbal Medicines,Plant Extract,Extract, Plant,Extracts, Plant,Medicines, Herbal
D011723 Chrysanthemum cinerariifolium A plant species of the genus CHRYSANTHEMUM, family ASTERACEAE. The flowers contain PYRETHRINS, cinerolones, and chrysanthemines which are powerful contact insecticides. Most in the old Pyrethrum genus are reclassified to TANACETUM; some to other ASTERACEAE genera. Pyrethrum,Pyrethum Daisy,Chrysanthemum coccineum,Tanacetum cinerariifolium,Tanacetum coccineum,Chrysanthemum cinerariifoliums,Chrysanthemum coccineums,Daisies, Pyrethum,Daisy, Pyrethum,Pyrethrums,Pyrethum Daisies,Tanacetum cinerariifoliums,Tanacetum coccineums,cinerariifolium, Chrysanthemum,cinerariifoliums, Tanacetum,coccineums, Chrysanthemum,coccineums, Tanacetum
D005243 Feces Excrement from the INTESTINES, containing unabsorbed solids, waste products, secretions, and BACTERIA of the DIGESTIVE SYSTEM.
D005260 Female Females
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia

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