Biomaterial Database

Itraconazole pulse: an overview of current use. 1998

D W Warnock

Mycology Reference Laboratory, Public Health Laboratory Service, Bristol.

Traditionally, fungal infections of the fingernails and toenails have been difficult to treat. Itraconazole is an orally administered triazole antifungal agent with a wide spectrum of activity against dermatophytes, yeasts and some moulds. Pulse therapy with itraconazole is an effective new treatment which offers the shortest treatment course with the least total number of treatment days and lowest total dose.

UI	MeSH Term	Description	Entries
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000935	Antifungal Agents	Substances that destroy fungi by suppressing their ability to grow or reproduce. They differ from FUNGICIDES, INDUSTRIAL because they defend against fungi present in human or animal tissues.	Anti-Fungal Agents,Antifungal Agent,Fungicides, Therapeutic,Antibiotics, Antifungal,Therapeutic Fungicides,Agent, Antifungal,Anti Fungal Agents,Antifungal Antibiotics
D014009	Onychomycosis	A fungal infection of the nail, usually caused by DERMATOPHYTES; YEASTS; or nondermatophyte MOLDS.	Nail Fungus,Tinea Unguium,Fungus, Nail,Onychomycoses
D017964	Itraconazole	A triazole antifungal agent that inhibits cytochrome P-450-dependent enzymes required for ERGOSTEROL synthesis.	Orungal,R-51211,Sporanox,R 51211,R51211