Biomaterial Database

Sinus histiocytosis with massive lymphadenopathy (Rosai-Dorfman disease). 1998

O F Unal, and S Köybaşi, and S Kaya

Department of Otolaryngology, Head & Neck Surgery, Hacettepe University Medical Faculty, Ankara, Turkey. ofunal@tr-net.net.tr

Sinus histiocytosis with massive lymphadenopathy (SHML) is a distinct clinicopathological entity described by Rosai and Dorfman and differentiated by other childhood histiocytoses by its distinct characteristics. This is a rare pathology and should be kept in mind for differential diagnosis of neck masses, especially in childhood. In this article a case with SHML is presented and clinical features of the disease given.

UI	MeSH Term	Description	Entries
D007223	Infant	A child between 1 and 23 months of age.	Infants
D008206	Lymphatic Diseases	Diseases of LYMPH; LYMPH NODES; or LYMPHATIC VESSELS.	Lymphatism,Status Lymphaticus,Disease, Lymphatic,Diseases, Lymphatic,Lymphatic Disease
D008297	Male		Males
D009333	Neck	The part of a human or animal body connecting the HEAD to the rest of the body.	Necks
D003937	Diagnosis, Differential	Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures.	Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D015618	Histiocytosis, Sinus	Benign, non-Langerhans-cell, histiocytic proliferative disorder that primarily affects the lymph nodes. It is often referred to as sinus histiocytosis with massive lymphadenopathy.	Destombes-Rosai-Dorfman Syndrome,Rosai-Dorfman Disease,Sinus Histiocytosis with Massive Lymphadenopathy,Destombes Rosai Dorfman Syndrome,Disease, Rosai-Dorfman,Histiocytoses, Sinus,Rosai Dorfman Disease,Sinus Histiocytoses,Sinus Histiocytosis,Syndrome, Destombes-Rosai-Dorfman