-transparent.png){kind=logo}
Solid-phase synthesis of a 300-member pharmacophore library of 1,4-dihydropyridines from keto ester, diketone and aldehyde building blocks on a cleavable amine polymeric support is described. Screening and serial deconvolution of the combinatorial library has resulted in identification of known and new potent calcium channel blockers.
Related Publications
M F Gordeev, and
D V Patel, and
B P England, and
S Jonnalagadda, and
J D Combs, and
E M Gordon
January 2008,
Prikladnaia biokhimiia i mikrobiologiia,
M F Gordeev, and
D V Patel, and
B P England, and
S Jonnalagadda, and
J D Combs, and
E M Gordon
November 1987,
Journal of clinical pharmacology,
M F Gordeev, and
D V Patel, and
B P England, and
S Jonnalagadda, and
J D Combs, and
E M Gordon
September 1986,
Journal of molecular and cellular cardiology,
M F Gordeev, and
D V Patel, and
B P England, and
S Jonnalagadda, and
J D Combs, and
E M Gordon
May 1994,
Proceedings of the National Academy of Sciences of the United States of America,
M F Gordeev, and
D V Patel, and
B P England, and
S Jonnalagadda, and
J D Combs, and
E M Gordon
January 2017,
Hypertension research : official journal of the Japanese Society of Hypertension,
M F Gordeev, and
D V Patel, and
B P England, and
S Jonnalagadda, and
J D Combs, and
E M Gordon
April 2024,
Journal of general internal medicine,
M F Gordeev, and
D V Patel, and
B P England, and
S Jonnalagadda, and
J D Combs, and
E M Gordon
May 2000,
Acta anaesthesiologica Scandinavica,
M F Gordeev, and
D V Patel, and
B P England, and
S Jonnalagadda, and
J D Combs, and
E M Gordon
December 1991,
Circulation,
M F Gordeev, and
D V Patel, and
B P England, and
S Jonnalagadda, and
J D Combs, and
E M Gordon
January 2005,
Archiwum medycyny sadowej i kryminologii,
M F Gordeev, and
D V Patel, and
B P England, and
S Jonnalagadda, and
J D Combs, and
E M Gordon
July 2014,
Pflugers Archiv : European journal of physiology,
