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BACKGROUND With the poor results of resective and fenestration procedures for polycystic liver disease (PCLD), we present the first series of patients receiving orthotopic liver transplantation for this condition. METHODS Five of our six patients with PCLD had polycystic kidney disease also. Three of these five received combined organ transplants, while the other two required subsequent kidney transplants. RESULTS Forty-eight and 52 months after orthotopic liver transplantation, all surviving patients had relief of their pain, distention, and anorexia. Two patients had succumbed to infectious complications and died at 15 and 24 months after transplant. CONCLUSIONS We conclude that patients with PCLD can be transplanted safely for the relief of their distention and anorexia, with good results. Those patients with both PCLD and polycystic kidney disease who are not dialysis dependent can be managed for several years with isolated liver transplantation and then receive kidney transplantation if needed. Those who are dialysis dependent should receive combined liver-kidney transplantation. Unfortunately, patients with polycystic disease seem to be very susceptible to infectious complications after organ transplantation.
D R Jeyarajah, and
T A Gonwa, and
G Testa, and
O Abbasoglu, and
R Goldstein, and
B S Husberg, and
M F Levy, and
G B Klintmalm
December 2019,
Transplant international : official journal of the European Society for Organ Transplantation,
D R Jeyarajah, and
T A Gonwa, and
G Testa, and
O Abbasoglu, and
R Goldstein, and
B S Husberg, and
M F Levy, and
G B Klintmalm
October 2021,
Gastroenterologia y hepatologia,
D R Jeyarajah, and
T A Gonwa, and
G Testa, and
O Abbasoglu, and
R Goldstein, and
B S Husberg, and
M F Levy, and
G B Klintmalm
July 1983,
Transplantation,
D R Jeyarajah, and
T A Gonwa, and
G Testa, and
O Abbasoglu, and
R Goldstein, and
B S Husberg, and
M F Levy, and
G B Klintmalm
December 1978,
Urology,
D R Jeyarajah, and
T A Gonwa, and
G Testa, and
O Abbasoglu, and
R Goldstein, and
B S Husberg, and
M F Levy, and
G B Klintmalm
March 2000,
Hong Kong medical journal = Xianggang yi xue za zhi,
D R Jeyarajah, and
T A Gonwa, and
G Testa, and
O Abbasoglu, and
R Goldstein, and
B S Husberg, and
M F Levy, and
G B Klintmalm
December 2014,
Journal of the American College of Surgeons,
D R Jeyarajah, and
T A Gonwa, and
G Testa, and
O Abbasoglu, and
R Goldstein, and
B S Husberg, and
M F Levy, and
G B Klintmalm
May 1990,
Archives of surgery (Chicago, Ill. : 1960),
D R Jeyarajah, and
T A Gonwa, and
G Testa, and
O Abbasoglu, and
R Goldstein, and
B S Husberg, and
M F Levy, and
G B Klintmalm
March 2001,
Liver transplantation : official publication of the American Association for the Study of Liver Diseases and the International Liver Transplantation Society,
D R Jeyarajah, and
T A Gonwa, and
G Testa, and
O Abbasoglu, and
R Goldstein, and
B S Husberg, and
M F Levy, and
G B Klintmalm
August 2015,
Pediatric nephrology (Berlin, Germany),
D R Jeyarajah, and
T A Gonwa, and
G Testa, and
O Abbasoglu, and
R Goldstein, and
B S Husberg, and
M F Levy, and
G B Klintmalm
November 2016,
Progres en urologie : journal de l'Association francaise d'urologie et de la Societe francaise d'urologie,
