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Relapses in the Guillain-Barré syndrome after treatment with intravenous immune globulin or plasma exchange. 1998
J G Romano, and
F T Rotta, and
P Potter, and
V Rosenfeld, and
R Santibanez, and
B Rocha, and
W G Bradley
Department of Neurology (D4-5), University of Miami School of Medicine, Florida 33101, USA.
To clarify the question of whether Guillain-Barré syndrome (GBS) patients treated with intravenous immune globulin (i.v.IG) relapse at a higher frequency than those treated with plasma exchange (PE), 54 patients with GBS were studied retrospectively. A higher frequency of relapses was noted in the PE-treated patients than in those receiving i.v.IG. The presence of an associated medical condition correlated with an increased risk of relapses, while earlier onset of treatment resulted in a decrease of relapses of GBS. This study found no support for prior suggestions of increased relapses in patients with GBS treated with i.v.IG as opposed to those treated with PE.
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