[The penicillin susceptibility of Streptococcus pneumoniae, Haemophilus influenzae, Moraxella catarrhalis and Staphylococcus aureus in persons suffering from upper respiratory tract infections]. 1998

K Hareńska, and G Janicka, and D Wojciechowska
Zakład Diagnostyki Mikrobiologicznej, Samodzielnego Publicznego Zespołu Opieki Zdrowotnej w Zninie.

The susceptibility to penicillin was tested in 293 strains of S. aureus, 162 strains of H. influenzae, 60 strains of M. catarrhalis and 77 strains of S. pneumoniae, isolated from persons suffering from upper respiratory tract infections. Penicillin susceptibility testing has been performed by the disc diffusion technique. Beta-lactamase production in the penicillin-resistant strains of H. influenzae, M. catarrhalis and S. aureus was detected with nitrocefin impregnated disc. In beta-lactamase positive strains, the susceptibility to amoxacillin/clavulanic acid (AMC) was determined. Nearly half (46.3%) of H. influenzae strains was resistan to ampicillin. In the remaining bacteria, the percentage of resistance was 2.6% for S. pneumoniae, 82.4% for M. catarrhalis and 88.1% for S. aureus strains. All strains resistant to penicillin (ampicillin) produced beta-lactamase and were AMC sensitive.

UI MeSH Term Description Entries
D010406 Penicillins A group of antibiotics that contain 6-aminopenicillanic acid with a side chain attached to the 6-amino group. The penicillin nucleus is the chief structural requirement for biological activity. The side-chain structure determines many of the antibacterial and pharmacological characteristics. (Goodman and Gilman's The Pharmacological Basis of Therapeutics, 8th ed, p1065) Antibiotics, Penicillin,Penicillin,Penicillin Antibiotics
D012141 Respiratory Tract Infections Invasion of the host RESPIRATORY SYSTEM by microorganisms, usually leading to pathological processes or diseases. Respiratory System Infections,Upper Respiratory Tract Infection,Upper Respiratory Tract Infections,Infections, Respiratory,Infections, Respiratory Tract,Infections, Upper Respiratory,Infections, Upper Respiratory Tract,Respiratory Infections,Upper Respiratory Infections,Infection, Respiratory System,Infection, Respiratory Tract,Respiratory Infection, Upper,Respiratory System Infection,Respiratory Tract Infection
D004198 Disease Susceptibility A constitution or condition of the body which makes the tissues react in special ways to certain extrinsic stimuli and thus tends to make the individual more than usually susceptible to certain diseases. Diathesis,Susceptibility, Disease,Diatheses,Disease Susceptibilities,Susceptibilities, Disease
D004352 Drug Resistance, Microbial The ability of microorganisms, especially bacteria, to resist or to become tolerant to chemotherapeutic agents, antimicrobial agents, or antibiotics. This resistance may be acquired through gene mutation or foreign DNA in transmissible plasmids (R FACTORS). Antibiotic Resistance,Antibiotic Resistance, Microbial,Antimicrobial Resistance, Drug,Antimicrobial Drug Resistance,Antimicrobial Drug Resistances,Antimicrobial Resistances, Drug,Drug Antimicrobial Resistance,Drug Antimicrobial Resistances,Drug Resistances, Microbial,Resistance, Antibiotic,Resistance, Drug Antimicrobial,Resistances, Drug Antimicrobial
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D001424 Bacterial Infections Infections by bacteria, general or unspecified. Bacterial Disease,Bacterial Infection,Infection, Bacterial,Infections, Bacterial,Bacterial Diseases

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