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Cell area, percentage of cells with more than one nucleolus, and percentage of cells with the nucleolus apposed to the nuclear membrane (marginated) were compared in the medial and lateral magnocellular portions of the paraventricular nucleus (PVN) during water deprivation and voluntary rehydration. Lateral cells were larger and had a greater percentage of cells with multiple nucleoli in all conditions of deprivation and rehydration. In addition laterals were found to have more cells with marginated nucleoli in these cells with only one nucleoli. Medial and lateral cells showed similar responses to deprivation and rehydration.
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