-transparent.png){kind=logo}
In previous studies, we demonstrated that in ANG II-treated rats, prevention of cardiac hypertrophy (CH) by enalapril was blunted by bradykinin (BK) blockade by Hoe140. The putative role of BK was assessed by chronic exogenous BK infusion and in 46 male Sprague-Dawley rats infused with ANG II. ANG II (200 ng/kg/min) alone and associated with BK at low (BKlow, 15 ng/kg/day), mid (BKmid, 100 ng/kg/day) and high doses (BKhigh, 100 ng/kg/min) were delivered by Alzet osmotic pumps for 10 days and compared to control animals (Veh). Values of systolic arterial pressure (SAP, mmHg) in conscious rats and heart weight (HW, mg/g bw) at the end of the study are reported below. Results were submitted to ANOVA and are expressed as mean +/- SEM.
J L Pasquié, and
A Herizi, and
B Jover, and
G du Cailar, and
A Mimran
September 1980,
Neuroendocrinology,
J L Pasquié, and
A Herizi, and
B Jover, and
G du Cailar, and
A Mimran
March 1986,
Biochimica et biophysica acta,
J L Pasquié, and
A Herizi, and
B Jover, and
G du Cailar, and
A Mimran
April 1984,
The American journal of physiology,
J L Pasquié, and
A Herizi, and
B Jover, and
G du Cailar, and
A Mimran
September 2000,
Japanese journal of pharmacology,
J L Pasquié, and
A Herizi, and
B Jover, and
G du Cailar, and
A Mimran
October 1999,
American journal of hypertension,
J L Pasquié, and
A Herizi, and
B Jover, and
G du Cailar, and
A Mimran
January 1986,
European journal of pharmacology,
J L Pasquié, and
A Herizi, and
B Jover, and
G du Cailar, and
A Mimran
March 1982,
Biulleten' eksperimental'noi biologii i meditsiny,
J L Pasquié, and
A Herizi, and
B Jover, and
G du Cailar, and
A Mimran
February 2005,
Regulatory peptides,
J L Pasquié, and
A Herizi, and
B Jover, and
G du Cailar, and
A Mimran
December 2001,
Clinical and experimental pharmacology & physiology,
J L Pasquié, and
A Herizi, and
B Jover, and
G du Cailar, and
A Mimran
August 1985,
The American journal of physiology,
