-transparent.png){kind=logo}
1. Specific alpha- and beta-adrenoreceptor agonists, phenylephrine and isoprenaline, were injected intraportally into the intact rat liver under direct microscopic observation by an in vivo transillumination technique. 2. The diameter of a hepatic sinusoid and the intra-sinusoidal erythrocyte velocity were quantitatively measured, and the sinusoidal volume flow was calculated from these two parameters. 3. Results show that phenylephrine causes a sinusoidal constriction and an increased sinusoidal blood flow, whereas isoprenaline causes the opposite effects on the sinusoids. 4. All the sinusoidal responses to phenylephrine and isoprenaline were dose-dependent and were possibly related to the direct effect of these drugs on the sinusoids.
A Koo, and
I Y Liang, and
K K Cheng
January 1991,
European journal of clinical pharmacology,
A Koo, and
I Y Liang, and
K K Cheng
June 1977,
British journal of pharmacology,
A Koo, and
I Y Liang, and
K K Cheng
March 2022,
Basic research in cardiology,
A Koo, and
I Y Liang, and
K K Cheng
November 1969,
Comptes rendus hebdomadaires des seances de l'Academie des sciences. Serie D: Sciences naturelles,
A Koo, and
I Y Liang, and
K K Cheng
October 1976,
Experientia,
A Koo, and
I Y Liang, and
K K Cheng
January 1996,
Journal of vascular and interventional radiology : JVIR,
A Koo, and
I Y Liang, and
K K Cheng
July 1973,
British journal of diseases of the chest,
A Koo, and
I Y Liang, and
K K Cheng
January 2023,
Frontiers in cell and developmental biology,
A Koo, and
I Y Liang, and
K K Cheng
December 2012,
Acta physiologica Hungarica,
A Koo, and
I Y Liang, and
K K Cheng
August 1978,
Naunyn-Schmiedeberg's archives of pharmacology,
