[Superior sagittal sinus thrombosis presenting with subarachnoid hemorrhage in a patient with aplastic anemia]. 1998

H Ohta, and Y Kinoshita, and M Hashimoto, and H Yamada, and E Urasaki, and A Yokota
Department of Neurosurgery, School of Medicine, University of Occupational and Environmental Health, Kitakyusyu, Japan.

A 54-year-old female, who had been treated for aplastic anemia by metenolone acetate since 1981, developed a sudden unconsciousness in September 1995. On admission, she was drowny, CT showed a subarachnoid hemorrhage (SAH) in the right Sylvian fissure. Angiography demonstrated a complete occlusion of the superior sagittal sinus. The SAH was assumed to be originated from rupture of the right Sylvian vein, which was irregularly dilated on angiography. The dural sinus thrombosis was thought to be caused by a long term use of metenolone acetate, and it was discontinued. But her platelet count dropped due to the aggravation of aplastic anemia, and she developed repeated hemorrhagic infarction. An active anticoagulant therapy for the dural sinus thrombosis was thought to be inappropriate because she had the aplastic anemia and the hemorrhagic infarction recurred. We have successfully treated this case by mild anticoagulant therapy with nafamostat mesilate (Futhan).

UI MeSH Term Description Entries
D008279 Magnetic Resonance Imaging Non-invasive method of demonstrating internal anatomy based on the principle that atomic nuclei in a strong magnetic field absorb pulses of radiofrequency energy and emit them as radiowaves which can be reconstructed into computerized images. The concept includes proton spin tomographic techniques. Chemical Shift Imaging,MR Tomography,MRI Scans,MRI, Functional,Magnetic Resonance Image,Magnetic Resonance Imaging, Functional,Magnetization Transfer Contrast Imaging,NMR Imaging,NMR Tomography,Tomography, NMR,Tomography, Proton Spin,fMRI,Functional Magnetic Resonance Imaging,Imaging, Chemical Shift,Proton Spin Tomography,Spin Echo Imaging,Steady-State Free Precession MRI,Tomography, MR,Zeugmatography,Chemical Shift Imagings,Echo Imaging, Spin,Echo Imagings, Spin,Functional MRI,Functional MRIs,Image, Magnetic Resonance,Imaging, Magnetic Resonance,Imaging, NMR,Imaging, Spin Echo,Imagings, Chemical Shift,Imagings, Spin Echo,MRI Scan,MRIs, Functional,Magnetic Resonance Images,Resonance Image, Magnetic,Scan, MRI,Scans, MRI,Shift Imaging, Chemical,Shift Imagings, Chemical,Spin Echo Imagings,Steady State Free Precession MRI
D008710 Methenolone A synthetic steroid that has been used for its anabolic action. Metenolone
D008875 Middle Aged An adult aged 45 - 64 years. Middle Age
D005260 Female Females
D006146 Guanidines A family of iminourea derivatives. The parent compound has been isolated from mushrooms, corn germ, rice hulls, mussels, earthworms, and turnip juice. Derivatives may have antiviral and antifungal properties.
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000741 Anemia, Aplastic A form of anemia in which the bone marrow fails to produce adequate numbers of peripheral blood elements. Anemia, Hypoplastic,Aplastic Anaemia,Aplastic Anemia,Anaemia, Aplastic,Aplastic Anaemias,Aplastic Anemias,Hypoplastic Anemia,Hypoplastic Anemias
D000925 Anticoagulants Agents that prevent BLOOD CLOTTING. Anticoagulant Agent,Anticoagulant Drug,Anticoagulant,Anticoagulant Agents,Anticoagulant Drugs,Anticoagulation Agents,Indirect Thrombin Inhibitors,Agent, Anticoagulant,Agents, Anticoagulant,Agents, Anticoagulation,Drug, Anticoagulant,Drugs, Anticoagulant,Inhibitors, Indirect Thrombin,Thrombin Inhibitors, Indirect
D001550 Benzamidines Amidines substituted with a benzene group. Benzamidine and its derivatives are known as peptidase inhibitors.
D012851 Sinus Thrombosis, Intracranial Formation or presence of a blood clot (THROMBUS) in the CRANIAL SINUSES, large endothelium-lined venous channels situated within the SKULL. Intracranial sinuses, also called cranial venous sinuses, include the superior sagittal, cavernous, lateral, petrous sinuses, and many others. Cranial sinus thrombosis can lead to severe HEADACHE; SEIZURE; and other neurological defects. Cranial Sinus Thrombosis,Intracranial Sinus Thrombophlebitis,Petrous Sinus Thrombosis,Sinus Thrombosis,Venous Sinus Thrombosis, Cranial,Petrous Sinus Thrombophlebitis,Cranial Sinus Thromboses,Intracranial Sinus Thrombophlebitides,Intracranial Sinus Thromboses,Intracranial Sinus Thrombosis,Petrous Sinus Thrombophlebitides,Petrous Sinus Thromboses,Sinus Thrombophlebitides, Intracranial,Sinus Thrombophlebitides, Petrous,Sinus Thrombophlebitis, Intracranial,Sinus Thrombophlebitis, Petrous,Sinus Thromboses,Sinus Thromboses, Cranial,Sinus Thromboses, Intracranial,Sinus Thromboses, Petrous,Sinus Thrombosis, Cranial,Sinus Thrombosis, Petrous,Thrombophlebitides, Intracranial Sinus,Thrombophlebitides, Petrous Sinus,Thrombophlebitis, Intracranial Sinus,Thrombophlebitis, Petrous Sinus,Thromboses, Cranial Sinus,Thromboses, Intracranial Sinus,Thromboses, Petrous Sinus,Thromboses, Sinus,Thrombosis, Cranial Sinus,Thrombosis, Intracranial Sinus,Thrombosis, Petrous Sinus,Thrombosis, Sinus

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