Biomaterial Database

Olfactory neuroblastoma (esthesioneuroblastoma) and esthesioneuroepithelioma: histologic and immunohistochemical study. 1998

A Taraszewska, and A Czorniuk-Sliwa, and M Dambska

Department of Neuropathology, Medical Research Centre, Polish Academy of Sciences, Warszawa.

Two cases of olfactory neuroblastoma (ONB) representing two morphological variants of the tumor are described. Case 1 exhibited a neuroblastoma-like histological pattern corresponding to the usually reported type of ONB--the esthesioneuroblastoma, whereas in case 2 a very rare variant of ONB-the esthesioneuroepithelioma was recognized. The histological and immunohistochemical differences between the cases are discussed with regard to still controversial opinions concerning the subclassification of ONB and the histogenesis and clinical prognosis of these tumors.

UI	MeSH Term	Description	Entries
D007150	Immunohistochemistry	Histochemical localization of immunoreactive substances using labeled antibodies as reagents.	Immunocytochemistry,Immunogold Techniques,Immunogold-Silver Techniques,Immunohistocytochemistry,Immunolabeling Techniques,Immunogold Technics,Immunogold-Silver Technics,Immunolabeling Technics,Immunogold Silver Technics,Immunogold Silver Techniques,Immunogold Technic,Immunogold Technique,Immunogold-Silver Technic,Immunogold-Silver Technique,Immunolabeling Technic,Immunolabeling Technique,Technic, Immunogold,Technic, Immunogold-Silver,Technic, Immunolabeling,Technics, Immunogold,Technics, Immunogold-Silver,Technics, Immunolabeling,Technique, Immunogold,Technique, Immunogold-Silver,Technique, Immunolabeling,Techniques, Immunogold,Techniques, Immunogold-Silver,Techniques, Immunolabeling
D008875	Middle Aged	An adult aged 45 - 64 years.	Middle Age
D009296	Nasal Cavity	The proximal portion of the respiratory passages on either side of the NASAL SEPTUM. Nasal cavities, extending from the nares to the NASOPHARYNX, are lined with ciliated NASAL MUCOSA.	Nasal Cavities,Cavities, Nasal,Cavity, Nasal
D009669	Nose Neoplasms	Tumors or cancer of the NOSE.	Cancer of Nose,Nasal Neoplasms,Nose Cancer,Cancer of the Nose,Nasal Cancer,Neoplasms, Nose,Cancer, Nasal,Cancer, Nose,Cancers, Nasal,Cancers, Nose,Nasal Cancers,Nasal Neoplasm,Neoplasm, Nasal,Neoplasm, Nose,Neoplasms, Nasal,Nose Cancers,Nose Neoplasm
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D018241	Neuroectodermal Tumors, Primitive, Peripheral	A group of highly cellular primitive round cell neoplasms which occur extracranially in soft tissue and bone and are derived from embryonal neural crest cells. These tumors occur primarily in children and adolescents and share a number of characteristics with EWING SARCOMA.	Neuroectodermal Tumor, Peripheral,Peripheral Primitive Neuroectodermal Tumor,Peripheral Primitive Neuroectodermal Tumors,(pPNET) Peripheral Primitive Neuroectodermal Tumors,Extracranial Primitive Neuroectodermal Tumor,Neuroectodermal Neoplasm, Peripheral Primitive,Neuroectodermal Tumor, Peripheral Primitive,Neuroepithelioma, Peripheral,Peripheral Primitive Neuroectodermal Neoplasm,Primitive Neuroectodermal Tumor, Extracranial,Neuroectodermal Tumors, Peripheral,Neuroepitheliomas, Peripheral,Peripheral Neuroectodermal Tumor,Peripheral Neuroectodermal Tumors,Peripheral Neuroepithelioma,Peripheral Neuroepitheliomas,Tumor, Peripheral Neuroectodermal,Tumors, Peripheral Neuroectodermal
D018304	Esthesioneuroblastoma, Olfactory	A malignant olfactory neuroblastoma arising from the olfactory epithelium of the superior nasal cavity and cribriform plate. It is uncommon (3% of nasal tumors) and rarely is associated with the production of excess hormones (e.g., SIADH, Cushing Syndrome). It has a high propensity for multiple local recurrences and bony metastases. (From Holland et al., Cancer Medicine, 3rd ed, p1245; J Laryngol Otol 1998 Jul;112(7):628-33)	Aesthesioneuroblastoma,Neuroblastoma, Olfactory,Olfactory Neuroblastoma,Paranasal Sinus-Nasal Cavity Esthesioneuroblastoma,Esthesioneuroblastoma,Esthesioneuroblastoma, Paranasal Sinus-Nasal Cavity,Aesthesioneuroblastomas,Esthesioneuroblastoma, Paranasal Sinus Nasal Cavity,Esthesioneuroblastomas,Esthesioneuroblastomas, Olfactory,Neuroblastomas, Olfactory,Olfactory Esthesioneuroblastoma,Olfactory Esthesioneuroblastomas,Olfactory Neuroblastomas,Paranasal Sinus Nasal Cavity Esthesioneuroblastoma