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The effects of 4--6 h head-out immersion on excretion of vanillylmandelic acid (VMA), blood pressure and plasma volume were estimated in 8 endurance-trained (TR) and 8 untrained (UT) subjects. In the trained only a slight increase of VMA excretion occurred (4 h value: +2.7 +/- 10.9 ng/ml GFR), but there was a highly significant increase in the UT (+29.0 +/- 17.2 ng/ml GFR). VMA values during control experiments in supine position tended to decrease in both groups. Systolic and diastolic blood pressure fell by 20 mm Hg after beginning of immersion; in the UT plasma volume was reduced while it remained constant in TR. The results indicate that orthostatic intolerance (o.i.) after immersion is not effected by decreased sympathetic innervation of vessels; in contrast it seems to be partly compensated for by an elevated sympathetic activity at least in the UT. As a main cause for the post-immersion o.i. one might suggest a decrease in renin activity.
W Skipka, and
K A Deck, and
D Böning
November 1963,
Ceskoslovenska gastroenterologie a vyziva,
W Skipka, and
K A Deck, and
D Böning
December 1972,
Lancet (London, England),
W Skipka, and
K A Deck, and
D Böning
October 1986,
British journal of industrial medicine,
W Skipka, and
K A Deck, and
D Böning
January 1969,
Psychosomatic medicine,
W Skipka, and
K A Deck, and
D Böning
January 1971,
Bratislavske lekarske listy,
W Skipka, and
K A Deck, and
D Böning
January 1966,
Sistema nervoso,
W Skipka, and
K A Deck, and
D Böning
October 1981,
Japanese journal of pharmacology,
W Skipka, and
K A Deck, and
D Böning
January 1989,
Laboratornoe delo,
W Skipka, and
K A Deck, and
D Böning
August 1968,
Schweizerische medizinische Wochenschrift,
W Skipka, and
K A Deck, and
D Böning
September 1968,
Fiziologicheskii zhurnal SSSR imeni I. M. Sechenova,
