Biomaterial Database

Physicomechanical and cytotoxic properties of room temperature vulcanizing silicone prosthetic elastomers. 1998

G L Polyzois, and A H Pettersen

Department of Removable Prosthodontics, School of Dentistry, University of Athens, Greece.

The physicomechanical and cytotoxic properties of two newly introduced room temperature vulcanizing (RTV) silicone prosthetic elastomers, Ideal and Silskin 2000, were investigated. Another RTV silicone, Elastosil M3500, was also investigated as a potential facial material. The in vitro cytotoxicity was assessed with the agar diffusion test and mouse fibroblast cells (L929). The properties investigated were tensile strength, percentage elongation, modulus, tear strength, hardness, and color changes (deltaE*). The properties tested were selected because of their clinical significance in fabricating facial prostheses. The results indicate that Elastosil M3500 has a better combination of high tear strength, elongation at break, and low hardness than Ideal and Silskin 2000. All materials demonstrated a low cytotoxic profile. Elastosil M3500 warrants further attention with clinical trials.

UI	MeSH Term	Description	Entries
D008447	Maxillofacial Prosthesis	A prosthetic appliance for the replacement of areas of the maxilla, mandible, and face, missing as a result of deformity, disease, injury, or surgery. When the prosthesis replaces portions of the mandible only, it is referred to as MANDIBULAR PROSTHESIS.	Maxillary Prosthesis,Maxillary Prostheses,Maxillofacial Prostheses,Prostheses, Maxillary,Prostheses, Maxillofacial,Prosthesis, Maxillary,Prosthesis, Maxillofacial
D011474	Prosthesis Design	The plan and delineation of prostheses in general or a specific prosthesis.	Design, Prosthesis,Designs, Prosthesis,Prosthesis Designs
D002478	Cells, Cultured	Cells propagated in vitro in special media conducive to their growth. Cultured cells are used to study developmental, morphologic, metabolic, physiologic, and genetic processes, among others.	Cultured Cells,Cell, Cultured,Cultured Cell
D002627	Chemistry, Physical	The study of CHEMICAL PHENOMENA and processes in terms of the underlying PHYSICAL PHENOMENA and processes.	Physical Chemistry,Chemistries, Physical,Physical Chemistries
D003116	Color	The visually perceived property of objects created by absorption or reflection of specific wavelengths of light.	Colors
D004058	Diffusion	The tendency of a gas or solute to pass from a point of higher pressure or concentration to a point of lower pressure or concentration and to distribute itself throughout the available space. Diffusion, especially FACILITATED DIFFUSION, is a major mechanism of BIOLOGICAL TRANSPORT.	Diffusions
D004548	Elasticity	Resistance and recovery from distortion of shape.
D005347	Fibroblasts	Connective tissue cells which secrete an extracellular matrix rich in collagen and other macromolecules.	Fibroblast
D006244	Hardness	The mechanical property of material that determines its resistance to force. HARDNESS TESTS measure this property.	Hardnesses
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man