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BACKGROUND Patients often undergo limited resection instead of lobectomy for non-small cell lung cancer because of a low preoperative forced expiratory volume in 1 second (FEV1). Our goal is to define criteria that will preoperatively identify a group of patients who will not lose further function after lobectomy. METHODS Patients who underwent lobectomy with a preoperative FEV1 of less than 80% of predicted were retrospectively identified. Data collected included preoperative and postoperative pulmonary function tests, age, sex, the lobe resected, and preoperative ventilation-perfusion scan result. RESULTS Thirty-two patients were included in this study. The median preoperative FEV1 was 60% of predicted (1.65 L) and the mean change in FEV1 was a loss of 7.8% after lobectomy. The patients were divided into two groups. Group 1 (n = 13) had a preoperative FEV1 of less than or equal to 60% of predicted (median, 49%; 1.35 L) combined with an FEV1 to forced vital capacity ratio of less than or equal to 0.6. Group 2 (n = 19) includes all other patients (median preoperative FEV1, 69% of predicted; 1.87 L). The mean changes in FEV1 after lobectomy were +3.7% and -15.7% for groups 1 and 2, respectively (p < 0.005). A chronic obstructive pulmonary disease index was defined and then calculated for each patient. The relationship between this index and the change in FEV1 after lobectomy for all 32 patients appears linear (r = -0.43; p = 0.015). CONCLUSIONS Patients with a very low preoperative FEV1 and FEV1 to forced vital capacity ratio are less likely to lose ventilatory function after lobectomy and may actually improve it.
R J Korst, and
R J Ginsberg, and
M Ailawadi, and
M S Bains, and
R J Downey, and
V W Rusch, and
D Stover
February 1990,
Chest,
R J Korst, and
R J Ginsberg, and
M Ailawadi, and
M S Bains, and
R J Downey, and
V W Rusch, and
D Stover
September 2009,
Monaldi archives for chest disease = Archivio Monaldi per le malattie del torace,
R J Korst, and
R J Ginsberg, and
M Ailawadi, and
M S Bains, and
R J Downey, and
V W Rusch, and
D Stover
November 1991,
Chest,
R J Korst, and
R J Ginsberg, and
M Ailawadi, and
M S Bains, and
R J Downey, and
V W Rusch, and
D Stover
July 1998,
Chest,
R J Korst, and
R J Ginsberg, and
M Ailawadi, and
M S Bains, and
R J Downey, and
V W Rusch, and
D Stover
September 2022,
JTCVS open,
R J Korst, and
R J Ginsberg, and
M Ailawadi, and
M S Bains, and
R J Downey, and
V W Rusch, and
D Stover
September 2018,
Chest,
R J Korst, and
R J Ginsberg, and
M Ailawadi, and
M S Bains, and
R J Downey, and
V W Rusch, and
D Stover
January 1994,
Chest,
R J Korst, and
R J Ginsberg, and
M Ailawadi, and
M S Bains, and
R J Downey, and
V W Rusch, and
D Stover
January 2021,
Current research in physiology,
R J Korst, and
R J Ginsberg, and
M Ailawadi, and
M S Bains, and
R J Downey, and
V W Rusch, and
D Stover
January 2016,
International journal of chronic obstructive pulmonary disease,
R J Korst, and
R J Ginsberg, and
M Ailawadi, and
M S Bains, and
R J Downey, and
V W Rusch, and
D Stover
June 1999,
Archivos de bronconeumologia,
