The onset of coronary arterial calcification is an active, organized, metabolically regulated process that occurs only when the initial changes of atherosclerosis are present. Coronary arterial calcification may represent an attempt to protect the arterial wall mechanically. Determination of hemodynamic significance in detecting coronary heart disease was the aim of the study. 110 patients with suspected angina pectoris were performed fluoroscopy and coronary angiography after-wards. In 77 patients (70%) was determined coronary arteriosclerosis using coronary angiography, and in 33 (30%), finding was normal. Out of 77 (70%) patients with positive funding in 44 patients (57.14%) calcifications were detect using fluoroscopy, while in 33 (42.86%) were not. Out of 33 (30%) patients without arteriosclerosis calcifications were detected in 5 (15.15%) patients, and in 28 (84.85%) were not. According to our results and literature review, the calcification finding confirms the presence of already existing significant stenosis on the coronary artery or a high risk for hemodynamic disorder within the next two to five years.