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OBJECTIVE To specify etiology and clinical course of nosocomial infectious endocarditis (IE) and IE of drug addicts (AIE). METHODS 8 cases of AIE and 27 IE cases after various invasive interventions (nosocomial endocarditis). RESULTS Among causing agents of IE and AIE were Staphylococcus aureus, Proteus, Escherichia coli, Pseudomonas aeruginosa, anaerobic microflora, pathogenic fungi. AIE is characterized by affection of the tricuspid valve, pulmonary artery thromboembolism. Among nosocomial endocarditides are frequent IE of the replaced valve, caused by infection of venous catheters, dental manipulations, chronic hemodialysis. IE and AIE are most frequently treated with the following antibiotics: ampicilin, gentamycin, augmentin, unasin, cephalosporins, rifadin, ciprofloxin, tienam. CONCLUSIONS Nosocomial IE and AIE have drawn much attention in the last decade because of development of new complex invasive treatments and expansion of narcomania.
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