The adenomas of Familial Polyposis Coli and of Gardner's syndrome are widely thought to affect the large bowel only. However, this report and a critical review of the literature shows that of the few hundred reported cases of these diseases, at least thirty-six have also shown gastric and/or small bowel polyps. The majority have been concentrated in stomach, duodenum and ampulla of Vater and the latter two areas have shown the highest incidence of carcinoma. It seems that gastric polyps are especially associated with Familial Polyposis Coli, and duodeno-ampullary ones with Gardner's syndrome.