-transparent.png){kind=logo}
OBJECTIVE To describe viral infection of the corneal endothelium in a patient with recurrent herpes simplex virus keratitis in the corneal graft. METHODS Case report. A healthy 28-year-old man presented with necrotizing stromal keratitis and corneal perforation in the corneal graft. A second penetrating keratoplasty was performed. The corneal button was processed for histopathologic, immunohistochemical, and electron microscopic studies. RESULTS Histopathologically, the corneal endothelium showed viral inclusion bodies. Herpes simplex virus antigens and viral particles were identified in stromal keratocytes and corneal endothelial cells. CONCLUSIONS Productive herpes simplex virus infection of the corneal endothelial cells may contribute to corneal graft failure in recurrent herpes simplex virus infections.
L M Holbach, and
N Asano, and
G O Naumann
May 1987,
[Zhonghua yan ke za zhi] Chinese journal of ophthalmology,
L M Holbach, and
N Asano, and
G O Naumann
June 1968,
Proceedings of the Royal Society of Medicine,
L M Holbach, and
N Asano, and
G O Naumann
October 1983,
American journal of ophthalmology,
L M Holbach, and
N Asano, and
G O Naumann
May 1983,
American journal of ophthalmology,
L M Holbach, and
N Asano, and
G O Naumann
February 1998,
The British journal of ophthalmology,
L M Holbach, and
N Asano, and
G O Naumann
November 1968,
Nippon Ganka Gakkai zasshi,
L M Holbach, and
N Asano, and
G O Naumann
December 2016,
Cornea,
L M Holbach, and
N Asano, and
G O Naumann
January 1988,
Eye (London, England),
L M Holbach, and
N Asano, and
G O Naumann
October 1974,
Nippon Ganka Gakkai zasshi,
L M Holbach, and
N Asano, and
G O Naumann
April 2010,
Expert review of ophthalmology,
