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[The development and certification of the Hepabest anti-HBc IgG test system for detecting antibodies to the core antigen of the hepatitis B virus]. 1998
O A Iaroslavtseva, and
I G Netesova, and
L I Karpenko, and
O V Mel'nikova, and
S A Zaĭtsev, and
A A Il'ichev
Joint Stock Company Vector-Best, Research Institute of Bioengineering, Koltsovo, Russia.
The comparison of the newly developed "HepaBest anti-HBc IgG" assay system for the detection of hepatitis B virus (HBV) core antigen with the reference system "ImmunoComb HBc IgG" (Orgenics, France-Israel) and its approbation on 91 serum samples from patients in the Infectious Clinical Hospital were carried out. The coincidence rate of the results obtained with the use of the two assay systems was 87.9%. The system "HepaBest anti-HBc IgG" permitted the detection of patients whose sera contained no other HBV markers, except anti-HBc IgG. This assay system may be recommended for use in clinical and epidemiological investigations for ascertaining the diagnosis.
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