Kinetics of indomethacin absorption, elimination, and enterohepatic circulation in man.
1976
K C Kwan, and
G O Breault, and
E R Umbenhauer, and
F G McMahon, and
D E Duggan
UI
MeSH Term
Description
Entries
D007213
Indomethacin
A non-steroidal anti-inflammatory agent (NSAID) that inhibits CYCLOOXYGENASE, which is necessary for the formation of PROSTAGLANDINS and other AUTACOIDS. It also inhibits the motility of POLYMORPHONUCLEAR LEUKOCYTES.
Uptake of substances through the lining of the INTESTINES.
Absorption, Intestinal
D007700
Kinetics
The rate dynamics in chemical or physical systems.
D004764
Enterohepatic Circulation
Recycling through liver by excretion in bile, reabsorption from intestines (INTESTINAL REABSORPTION) into portal circulation, passage back into liver, and re-excretion in bile.