New closed-form expressions for the estimation of arterial windkessel compliance. 1998

G Gnudi
Department of Electronics Informatics and Systems (DEIS), University of Bologna, Italy. ggnudi@deis.unibo.it

New closed-form mathematical expressions, in the time- and frequency-domain, are derived for estimating the arterial windkessel compliance. The proposed expressions assume the three-element windkessel to model the arterial system and require the measurements of the entire waveforms of arterial pressure and flow. The resistance parameters are estimated using the recently proposed energy-balance method, then compliance is analytically calculated in order to minimize the pressure error in the compliant element. The derived expressions remain valid even when the windkessel compliance is assumed to be pressure-dependent. Also, it is shown that the method, either time- or frequency-domain formulation, provides parameter estimates, which minimize the arterial pressure square error. The method has been applied to simulated data as well as to pressure and flow data measured in the ascending aorta of three anaesthetized dogs under different circulatory conditions.

UI MeSH Term Description Entries
D008955 Models, Cardiovascular Theoretical representations that simulate the behavior or activity of the cardiovascular system, processes, or phenomena; includes the use of mathematical equations, computers and other electronic equipment. Cardiovascular Model,Cardiovascular Models,Model, Cardiovascular
D012039 Regional Blood Flow The flow of BLOOD through or around an organ or region of the body. Blood Flow, Regional,Blood Flows, Regional,Flow, Regional Blood,Flows, Regional Blood,Regional Blood Flows
D001775 Blood Circulation The movement of the BLOOD as it is pumped through the CARDIOVASCULAR SYSTEM. Blood Flow,Circulation, Blood,Blood Flows,Flow, Blood
D001794 Blood Pressure PRESSURE of the BLOOD on the ARTERIES and other BLOOD VESSELS. Systolic Pressure,Diastolic Pressure,Pulse Pressure,Pressure, Blood,Pressure, Diastolic,Pressure, Pulse,Pressure, Systolic,Pressures, Systolic
D004285 Dogs The domestic dog, Canis familiaris, comprising about 400 breeds, of the carnivore family CANIDAE. They are worldwide in distribution and live in association with people. (Walker's Mammals of the World, 5th ed, p1065) Canis familiaris,Dog
D000465 Algorithms A procedure consisting of a sequence of algebraic formulas and/or logical steps to calculate or determine a given task. Algorithm
D000818 Animals Unicellular or multicellular, heterotrophic organisms, that have sensation and the power of voluntary movement. Under the older five kingdom paradigm, Animalia was one of the kingdoms. Under the modern three domain model, Animalia represents one of the many groups in the domain EUKARYOTA. Animal,Metazoa,Animalia
D001011 Aorta The main trunk of the systemic arteries. Aortas
D001158 Arteries The vessels carrying blood away from the heart. Artery
D013997 Time Factors Elements of limited time intervals, contributing to particular results or situations. Time Series,Factor, Time,Time Factor

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