-transparent.png){kind=logo}
A brief electrical stimulation of the substantia nigra induced a marked and long lasting inhibition of the somatosensory evoked potentials recorded from the centrum medianum of the thalamus (CM) and posterior hypothalamic area (PHA) following sciatic stimulation in unanesthetized rabbits. The nigral inhibitory effect on CM was prolonged by the administration of morphine (4 mg/kg i.v.) but not influenced by that of methotrimeprazine (2-4 mg/kg i.v.). In contrast, the nigral inhibitory effect on PHA was enhanced by the injection of methotrimeprazine (2 mg/kg i.v.), but not changed by that of morphine (4 mg/kg i.v.). These results indicate that the inhibitory system originating from the substantia nigra operates on the somatosensory transmissions from the peripheral nerve to the thalamus and hypothalamus, and that morphine or methotrimeprazine in small doses induced a selective potentiation of the nigral inhibitory influence on the thalamus or hypothalamus, respectively.
H Kuromi, and
M Satoh, and
H Takagi
December 1973,
European journal of pharmacology,
H Kuromi, and
M Satoh, and
H Takagi
May 1976,
Electroencephalography and clinical neurophysiology,
H Kuromi, and
M Satoh, and
H Takagi
November 1977,
Experientia,
H Kuromi, and
M Satoh, and
H Takagi
November 1984,
Electroencephalography and clinical neurophysiology,
H Kuromi, and
M Satoh, and
H Takagi
January 1980,
Applied neurophysiology,
H Kuromi, and
M Satoh, and
H Takagi
November 1974,
Brain research,
H Kuromi, and
M Satoh, and
H Takagi
January 1993,
Functional neurology,
H Kuromi, and
M Satoh, and
H Takagi
January 1982,
Experimental brain research,
H Kuromi, and
M Satoh, and
H Takagi
November 1987,
British journal of anaesthesia,
H Kuromi, and
M Satoh, and
H Takagi
February 2000,
Muscle & nerve,
