Biomaterial Database

Gingival and mandibular bone necrosis caused by a paraformaldehyde-containing paste. 1998

R Di Felice, and T Lombardi

Department of Prosthodontics, School of Dentistry, University of Ferrara, Italy.

A paraformaldehyde preparation (Toxavit) was applied to an inflamed and symptomatic pulp of the mandibular right first molar (tooth #46), in a 30-year-old woman. Leakage from the product was responsible for marked necrosis of the gingiva and the alveolar cortical bone, which resulted in loss of the tooth.

UI	MeSH Term	Description	Entries
D008336	Mandibular Diseases	Diseases involving the MANDIBLE.	Disease, Mandibular,Diseases, Mandibular,Mandibular Disease
D009336	Necrosis	The death of cells in an organ or tissue due to disease, injury or failure of the blood supply.
D010020	Osteonecrosis	Death of a bone or part of a bone, either atraumatic or posttraumatic.	Aseptic Necrosis of Bone,Avascular Necrosis of Bone,Kienbock Disease,Necrosis, Aseptic, of Bone,Necrosis, Avascular, of Bone,Bone Necrosis,Kienbock's Disease,Kienboeck Disease,Kienboeck's Disease,Bone Aseptic Necrosis,Bone Avascular Necrosis,Bone Necroses,Kienboecks Disease,Necroses, Bone,Necrosis, Bone,Osteonecroses
D011108	Polymers	Compounds formed by the joining of smaller, usually repeating, units linked by covalent bonds. These compounds often form large macromolecules (e.g., BIOPOLYMERS; PLASTICS).	Polymer
D003787	Dental Pulp Devitalization	The destruction of the vitality of the pulp of the tooth. (From Jablonski, Dictionary of Dentistry, 1992, p243)	Devitalization, Dental Pulp,Pulp Devitalization, Dental
D005260	Female		Females
D005557	Formaldehyde	A highly reactive aldehyde gas formed by oxidation or incomplete combustion of hydrocarbons. In solution, it has a wide range of uses: in the manufacture of resins and textiles, as a disinfectant, and as a laboratory fixative or preservative. Formaldehyde solution (formalin) is considered a hazardous compound, and its vapor toxic. (From Reynolds, Martindale The Extra Pharmacopoeia, 30th ed, p717)	Formalin,Formol,Methanal,Oxomethane
D005882	Gingival Diseases	Diseases involving the GINGIVA.	Epulis,Gingivosis,Epulides,Disease, Gingival,Diseases, Gingival,Gingival Disease,Gingivoses
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328	Adult	A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available.	Adults