Orphenadrine overdose treated with physostigmine. 1976

B D Snyder, and M Kane, and D Plocher

UI MeSH Term Description Entries
D008297 Male Males
D009966 Orphenadrine A muscarinic antagonist used to treat drug-induced parkinsonism and to relieve pain from muscle spasm. Methyldiphenylhydramine,Disipal,Lysantin,Mefenamine,Mephenamine,Norflex,Norflex Orphenadrine Citrate,Orphenadrine Citrate,Orphenadrine Hydrochloride,Sodium Mefenamine,Citrate, Norflex Orphenadrine,Citrate, Orphenadrine,Hydrochloride, Orphenadrine,Mefenamine, Sodium,Orphenadrine Citrate, Norflex
D010830 Physostigmine A cholinesterase inhibitor that is rapidly absorbed through membranes. It can be applied topically to the conjunctiva. It also can cross the blood-brain barrier and is used when central nervous system effects are desired, as in the treatment of severe anticholinergic toxicity. Eserine
D003693 Delirium A disorder characterized by CONFUSION; inattentiveness; disorientation; ILLUSIONS; HALLUCINATIONS; agitation; and in some instances autonomic nervous system overactivity. It may result from toxic/metabolic conditions or structural brain lesions. (From Adams et al., Principles of Neurology, 6th ed, pp411-2) Delirium of Mixed Origin,Subacute Delirium,Delirium, Subacute,Deliriums, Subacute,Mixed Origin Delirium,Mixed Origin Deliriums,Subacute Deliriums
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000328 Adult A person having attained full growth or maturity. Adults are of 19 through 44 years of age. For a person between 19 and 24 years of age, YOUNG ADULT is available. Adults

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