Perinatal outcome of babies born to black South African women with hypertension. 1998

N M Rankhethoa, and J Moodley, and M Adhikari, and E Gouws
Department of Paediatrics and Child Health and MRC Biostatistics, Faculty of Medicine, University of Natal, Durban.

BACKGROUND Perinatal mortality rates (PMR) associated with hypertension are known to be high but there have been isolated reports that primigravidae who develop hypertension late in pregnancy have a better PMR than normotensive gravid women. OBJECTIVE To verify this report and compare the perinatal outcome in differing categories of hypertensive disorders of pregnancy. METHODS Maternal and neonatal data were recorded for all hypertensive patients admitted to King Edward VIII Hospital over a six month period from January to June 1995. In addition, similar data from normotensive women matched for age, parity and gestational age were also recorded. The latter formed the control group. RESULTS Three hundred and thirty seven women were entered into the study. Group A consisted of 189 patients with hypertension, while group B consisted of 148 normotensive pregnant women. There were no significant differences between the groups in relation to maternal age and parity. More women in the hypertensive group had Caesarean sections than in the control group (study group 115 versus control 35: p = 0.001). The perinatal outcome (SBs + NNDs) was significantly greater in the control group than in the hypertensive group (p = 0.031). More importantly, the number of perinatal deaths in the aproteinuric group was significantly different from the control group (aproteinuric group = 2; control group = 26, p = 0.007). Furthermore, the hypertensive group had greater foetal weights than the control groups (controls 1.65 kg versus 2.3 kg hypertensives: p = 0.0001). CONCLUSIONS This study shows that babies born to hypertensive mothers have a significantly greater birthweight than a control group of normotensive women. Further, although there are no statistically significant differences in perinatal outcome between moderate and severe categories of hypertension and control patients, there were significantly fewer perinatal deaths in women with aproteinuric hypertension.

UI MeSH Term Description Entries
D006973 Hypertension Persistently high systemic arterial BLOOD PRESSURE. Based on multiple readings (BLOOD PRESSURE DETERMINATION), hypertension is currently defined as when SYSTOLIC PRESSURE is consistently greater than 140 mm Hg or when DIASTOLIC PRESSURE is consistently 90 mm Hg or more. Blood Pressure, High,Blood Pressures, High,High Blood Pressure,High Blood Pressures
D007231 Infant, Newborn An infant during the first 28 days after birth. Neonate,Newborns,Infants, Newborn,Neonates,Newborn,Newborn Infant,Newborn Infants
D011203 Poverty A situation in which the level of living of an individual, family, or group is below the standard of the community. It is often related to a specific income level. Federal Poverty Level,Federal Poverty Threshold,Indigency,Low-Income Population,Absolute Poverty,Extreme Poverty,Indigents,Low Income Population,Federal Poverty Levels,Indigent,Level, Federal Poverty,Low Income Populations,Low-Income Populations,Population, Low Income,Population, Low-Income,Poverty Level, Federal,Poverty Threshold, Federal,Poverty, Absolute,Poverty, Extreme
D011247 Pregnancy The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH. Gestation,Pregnancies
D011248 Pregnancy Complications Conditions or pathological processes associated with pregnancy. They can occur during or after pregnancy, and range from minor discomforts to serious diseases that require medical interventions. They include diseases in pregnant females, and pregnancies in females with diseases. Adverse Birth Outcomes,Complications, Pregnancy,Adverse Birth Outcome,Birth Outcome, Adverse,Complication, Pregnancy,Outcome, Adverse Birth,Pregnancy Complication
D011256 Pregnancy Outcome Results of conception and ensuing pregnancy, including LIVE BIRTH; STILLBIRTH; or SPONTANEOUS ABORTION. The outcome may follow natural or artificial insemination or any of the various ASSISTED REPRODUCTIVE TECHNIQUES, such as EMBRYO TRANSFER or FERTILIZATION IN VITRO. Outcome, Pregnancy,Outcomes, Pregnancy,Pregnancy Outcomes
D001724 Birth Weight The mass or quantity of heaviness of an individual at BIRTH. It is expressed by units of pounds or kilograms. Birthweight,Birth Weights,Birthweights,Weight, Birth,Weights, Birth
D001741 Black or African American A person having origins in any of the black racial groups of Africa (https://www.federalregister.gov/documents/1997/10/30/97-28653/revisions-to-the-standards-for-the classification-of-federal-data-on-race-and-ethnicity). In the United States it is used for classification of federal government data on race and ethnicity. Race and ethnicity terms are self-identified social construct and may include terms outdated and offensive in MeSH to assist users who are interested in retrieving comprehensive search results for studies such as in longitudinal studies. African American,African Americans,African-American,Afro-American,Afro-Americans,Black Americans,Blacks,Negroes,African-Americans,Negro,Afro American,Afro Americans,American, African,American, Black,Black American
D002585 Cesarean Section Extraction of the FETUS by means of abdominal HYSTEROTOMY. Abdominal Delivery,Delivery, Abdominal,C-Section (OB),Caesarean Section,Postcesarean Section,Abdominal Deliveries,C Section (OB),C-Sections (OB),Caesarean Sections,Cesarean Sections,Deliveries, Abdominal
D005260 Female Females

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