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This report describes the glycosaminoglycans, collagen and elastin--composition of leiomyosarcoma. Studies were performed on leiomyosarcoma removed during surgery. The material was taken from 7 patients. Rearrangement of extracellular matrix in leiomyosarcoma has been found. There was an increase of total collagen content in comparison to control uterus. In both tissues type I collagen was found to be the predominant one. Both tissues, normal and neoplastic contain all known glycosaminoglycans types. Among them heparan sulphate was found to be the most abundant. A slight decrease in the content of this glycosaminoglycan was observed in leiomyosarcoma. A possible role of these alterations in tumour biology is discussed.
K Sobolewski, and
M Wolańska, and
M Drozdzewicz
June 2003,
Acta oto-laryngologica,
K Sobolewski, and
M Wolańska, and
M Drozdzewicz
June 2002,
Seminars in cancer biology,
K Sobolewski, and
M Wolańska, and
M Drozdzewicz
September 1995,
Experientia,
K Sobolewski, and
M Wolańska, and
M Drozdzewicz
December 1989,
The American journal of physiology,
K Sobolewski, and
M Wolańska, and
M Drozdzewicz
March 1996,
Nihon yakurigaku zasshi. Folia pharmacologica Japonica,
K Sobolewski, and
M Wolańska, and
M Drozdzewicz
January 2013,
International review of neurobiology,
K Sobolewski, and
M Wolańska, and
M Drozdzewicz
March 1998,
Cell adhesion and communication,
K Sobolewski, and
M Wolańska, and
M Drozdzewicz
January 1994,
Methods in enzymology,
K Sobolewski, and
M Wolańska, and
M Drozdzewicz
January 1994,
Methods in enzymology,
K Sobolewski, and
M Wolańska, and
M Drozdzewicz
January 1977,
Society of General Physiologists series,
