Biomaterial Database

Pediatric tuberculosis in rural South Africa--value of directly observed therapy. 1998

D Wilkinson, and G R Davies

Centre for Epidemiological Research, South African Medical Research Council, Mtubatuba, South Africa.

Tuberculosis is a major cause of mortality and morbidity among children in resource-poor settings. A strategy of community-based, directly observed therapy employed in a rural health district in South Africa since 1991 is described. Most children (75 per cent) diagnosed with tuberculosis were treated in the community and most of them (85 per cent) completed treatment. Supervision was either by clinic-based health workers (26 per cent), community health workers (20 per cent), or volunteer lay people (46 per cent). Among children diagnosed with tuberculosis who were also HIV infected, the case-fatality rate was higher than among the HIV uninfected, and a larger proportion of the HIV infected failed to complete treatment.

UI	MeSH Term	Description	Entries
D007223	Infant	A child between 1 and 23 months of age.	Infants
D008297	Male		Males
D010349	Patient Compliance	Voluntary cooperation of the patient in following a prescribed regimen.	Client Adherence,Client Compliance,Non-Adherent Patient,Patient Adherence,Patient Cooperation,Patient Noncompliance,Patient Non-Adherence,Patient Non-Compliance,Patient Nonadherence,Therapeutic Compliance,Treatment Compliance,Adherence, Client,Adherence, Patient,Client Compliances,Compliance, Client,Compliance, Patient,Compliance, Therapeutic,Compliance, Treatment,Cooperation, Patient,Non Adherent Patient,Non-Adherence, Patient,Non-Adherent Patients,Non-Compliance, Patient,Nonadherence, Patient,Noncompliance, Patient,Patient Non Adherence,Patient Non Compliance,Patient, Non-Adherent,Therapeutic Compliances,Treatment Compliances
D002648	Child	A person 6 to 12 years of age. An individual 2 to 5 years old is CHILD, PRESCHOOL.	Children
D002675	Child, Preschool	A child between the ages of 2 and 5.	Children, Preschool,Preschool Child,Preschool Children
D003153	Community Health Services	Diagnostic, therapeutic and preventive health services provided for individuals in the community.	Community Health Care,Community Healthcare,Health Services, Community,Services, Community Health,Community Health Service,Health Care, Community,Health Service, Community,Healthcare, Community,Service, Community Health
D005260	Female		Females
D006801	Humans	Members of the species Homo sapiens.	Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000293	Adolescent	A person 13 to 18 years of age.	Adolescence,Youth,Adolescents,Adolescents, Female,Adolescents, Male,Teenagers,Teens,Adolescent, Female,Adolescent, Male,Female Adolescent,Female Adolescents,Male Adolescent,Male Adolescents,Teen,Teenager,Youths
D000995	Antitubercular Agents	Drugs used in the treatment of tuberculosis. They are divided into two main classes: "first-line" agents, those with the greatest efficacy and acceptable degrees of toxicity used successfully in the great majority of cases; and "second-line" drugs used in drug-resistant cases or those in which some other patient-related condition has compromised the effectiveness of primary therapy.	Anti-Tuberculosis Agent,Anti-Tuberculosis Agents,Anti-Tuberculosis Drug,Anti-Tuberculosis Drugs,Antitubercular Agent,Antitubercular Drug,Tuberculostatic Agent,Tuberculostatic Agents,Antitubercular Drugs,Agent, Anti-Tuberculosis,Agent, Antitubercular,Agent, Tuberculostatic,Anti Tuberculosis Agent,Anti Tuberculosis Agents,Anti Tuberculosis Drug,Anti Tuberculosis Drugs,Drug, Anti-Tuberculosis,Drug, Antitubercular

Related Publications

D Wilkinson, and G R Davies

Directly observed therapy (DOT) for tuberculosis in South Africa--a reality?

August 1997, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,

D Wilkinson, and G R Davies

Evaluation of directly observed therapy for tuberculosis in KwaZulu-Natal, South Africa.

June 2009, Transactions of the Royal Society of Tropical Medicine and Hygiene,

D Wilkinson, and G R Davies

Unpaid community volunteers--effective providers of directly observed therapy (DOT) in rural South Africa.

April 2002, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde,

D Wilkinson, and G R Davies

Directly observed therapy for tuberculosis given twice weekly in the workplace in urban South Africa.

January 1997, Transactions of the Royal Society of Tropical Medicine and Hygiene,

D Wilkinson, and G R Davies

Voluntary lay supervisors of directly observed therapy for tuberculosis in Africa.

April 1998, Tropical doctor,

D Wilkinson, and G R Davies

Tuberculosis patient care decentralised to district clinics with community-based directly observed treatment in a rural district of South Africa.

May 1999, The international journal of tuberculosis and lung disease : the official journal of the International Union against Tuberculosis and Lung Disease,

D Wilkinson, and G R Davies

Directly observed therapy for tuberculosis.

April 1999, American journal of public health,

D Wilkinson, and G R Davies

Directly observed therapy for tuberculosis.

March 1996, BMJ (Clinical research ed.),

D Wilkinson, and G R Davies

Directly observed therapy for tuberculosis.

October 1996, The Western journal of medicine,

D Wilkinson, and G R Davies

Comparison of cost effectiveness of directly observed treatment (DOT) and conventionally delivered treatment for tuberculosis: experience from rural South Africa.

November 1997, BMJ (Clinical research ed.),