Epithelioid cell Spitz nevus of the eyelid. 1998

P Hiscott, and B Seitz, and G O Naumann
Department of Ophthalmology, University of Erlangen-Nurnberg, Erlangen, Germany.

OBJECTIVE To report a 20-month-old child with a rapidly growing dome-shaped red nodule on the left lower eyelid. The lesion was diagnosed clinically as an hemangioma, but microscopy disclosed an epithelioid Spitz nevus. METHODS Case report. RESULTS Histopathologic examination of the excised lesion disclosed a Spitz nevus (benign juvenile melanoma) of a chiefly epithelioid cell type. CONCLUSIONS The differential diagnosis of eyelid skin nodules in children should include Spitz nevus. This uncommon nevus has many cytologic features in common with nodular malignant melanoma. Histologically, it may be difficult to distinguish between nodular malignant melanoma and Spitz nevus.

UI MeSH Term Description Entries
D007223 Infant A child between 1 and 23 months of age. Infants
D003937 Diagnosis, Differential Determination of which one of two or more diseases or conditions a patient is suffering from by systematically comparing and contrasting results of diagnostic measures. Diagnoses, Differential,Differential Diagnoses,Differential Diagnosis
D005142 Eyelid Neoplasms Tumors of cancer of the EYELIDS. Eyelid Neoplasm,Neoplasm, Eyelid,Neoplasms, Eyelid
D005260 Female Females
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D012878 Skin Neoplasms Tumors or cancer of the SKIN. Cancer of Skin,Skin Cancer,Cancer of the Skin,Neoplasms, Skin,Cancer, Skin,Cancers, Skin,Neoplasm, Skin,Skin Cancers,Skin Neoplasm
D018332 Nevus, Epithelioid and Spindle Cell A benign compound nevus occurring most often in children before puberty, composed of spindle and epithelioid cells located mainly in the dermis, sometimes in association with large atypical cells and multinucleate cells, and having a close histopathological resemblance to malignant melanoma. The tumor presents as a smooth to slightly scaly, round to oval, raised, firm papule or nodule, ranging in color from pink-tan to purplish red, often with surface telangiectasia. (Dorland, 27th ed) Nevus, Spindle Cell and Epithelioid,Spitz Nevus,Nevus, Spitz

Related Publications

P Hiscott, and B Seitz, and G O Naumann
March 1993, Journal of the American Academy of Dermatology,
P Hiscott, and B Seitz, and G O Naumann
January 1994, Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie,
P Hiscott, and B Seitz, and G O Naumann
December 1990, Archives of dermatology,
P Hiscott, and B Seitz, and G O Naumann
January 2004, Southern medical journal,
P Hiscott, and B Seitz, and G O Naumann
January 1985, Zeitschrift fur Hautkrankheiten,
P Hiscott, and B Seitz, and G O Naumann
January 1985, Zeitschrift fur Hautkrankheiten,
P Hiscott, and B Seitz, and G O Naumann
January 1997, Dermatology (Basel, Switzerland),
P Hiscott, and B Seitz, and G O Naumann
January 1989, Virchows Archiv. A, Pathological anatomy and histopathology,
P Hiscott, and B Seitz, and G O Naumann
January 2016, Survey of ophthalmology,
Copied contents to your clipboard!