-transparent.png){kind=logo}
The present study investigated a possible relationship between plasma neurotensin (NT) and serum growth hormone (GH) levels after GH-stimulation provocative tests in humans. Samples were obtained from twelve prepubertal children and sixteen normal adult volunteers. Basal plasma NT levels were higher in children with growth delay (19.02 +/- 4.01 fmol/ml) (mean +/- SEM) than in normal adults (6.13 +/- 1.1 fmol/ml) (p < 0.001). Basal GH levels in children (1.52 +/- 0.06 ng/ml) were not different from those in adults (0.60 +/- 0.41 ng/ml). After stimulation of GH secretion, NT values decreased when GH peaked, and increased when GH levels diminished. These data suggest that plasma NT levels may be involved in the regulation of GH secretion, as a peripheral signal, probably through modulation of somatostatin release from the median eminence.
M Bozzola, and
A N Thome, and
E Giraldi, and
A M Lhiaubet, and
R M Schimpff
January 1972,
Clinical endocrinology,
M Bozzola, and
A N Thome, and
E Giraldi, and
A M Lhiaubet, and
R M Schimpff
February 1992,
Endocrinologia japonica,
M Bozzola, and
A N Thome, and
E Giraldi, and
A M Lhiaubet, and
R M Schimpff
November 1987,
Clinical endocrinology,
M Bozzola, and
A N Thome, and
E Giraldi, and
A M Lhiaubet, and
R M Schimpff
January 1993,
Hormone research,
M Bozzola, and
A N Thome, and
E Giraldi, and
A M Lhiaubet, and
R M Schimpff
June 1988,
Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.),
M Bozzola, and
A N Thome, and
E Giraldi, and
A M Lhiaubet, and
R M Schimpff
May 1996,
Journal of endocrinological investigation,
M Bozzola, and
A N Thome, and
E Giraldi, and
A M Lhiaubet, and
R M Schimpff
September 1987,
Clinical endocrinology,
M Bozzola, and
A N Thome, and
E Giraldi, and
A M Lhiaubet, and
R M Schimpff
June 1995,
European journal of pediatrics,
M Bozzola, and
A N Thome, and
E Giraldi, and
A M Lhiaubet, and
R M Schimpff
October 1985,
International journal of andrology,
M Bozzola, and
A N Thome, and
E Giraldi, and
A M Lhiaubet, and
R M Schimpff
January 1992,
The Turkish journal of pediatrics,
