Wearable microdialysis system for continuous in vivo monitoring of glucose. 1998

T Vering, and S Adam, and H Drewer, and C Dumschat, and R Steinkuhl, and A Schulze, and E G Siegel, and M Knoll
Institut für Chemo- und Biosensorik e.V., Münster, Germany.

We developed a new system to monitor glucose continuously in vivo. The miniaturised system is very easy to handle and was optimised to a resource-saving working modus. Sampling was performed by means of a biocompatible microdialysis needle probe inserted into the subcutaneous tissue. During glucose tolerance tests the results of our monitoring system were correlated with the glucose level of the venous blood stream. A comparison according to the procedure known as 'error grid analysis' provided an excellent correlation between the two completely independent analyses systems with the reference determination results. All values obtained with our systems were clinically correct or at least clinically acceptable.

UI MeSH Term Description Entries
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D015190 Blood Glucose Self-Monitoring Self evaluation of whole blood glucose levels outside the clinical laboratory. A digital or battery-operated reflectance meter may be used. It has wide application in controlling unstable insulin-dependent diabetes. Blood Sugar Self-Monitoring,Home Blood Glucose Monitoring,Monitoring, Home Blood Glucose,Self-Monitoring, Blood Glucose,Glucose, Blood, Self Monitoring,Glucose, Blood, Self-Monitoring,Blood Glucose Self Monitoring,Blood Glucose Self-Monitorings,Blood Sugar Self Monitoring,Blood Sugar Self-Monitorings,Glucose Self-Monitoring, Blood,Glucose Self-Monitorings, Blood,Self Monitoring, Blood Glucose,Self-Monitoring, Blood Sugar,Self-Monitorings, Blood Glucose,Self-Monitorings, Blood Sugar,Sugar Self-Monitoring, Blood,Sugar Self-Monitorings, Blood
D017551 Microdialysis A technique for measuring extracellular concentrations of substances in tissues, usually in vivo, by means of a small probe equipped with a semipermeable membrane. Substances may also be introduced into the extracellular space through the membrane.

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