[Ulcerative colitis--late functional results of ileoanal pouch anastomosis]. 1998

V Schumpelick, and S Willis, and E Schippers
Chirurgische Universitätsklinik und Poliklinik, RWTH Aachen.

Stool frequency after ileal pouch-anal anastomosis (IPAA) is about 5/day after adaptation during the first year. It depends on stool volume and pouch capacity, not on the design of the pouch. In most cases evacuation is spontaneous and as complete as in healthy rectum. 67% of patients are perfectly continent, while 19% have to wear pads due to intermittent leakage. Complete incontinence is reported in 0-4% of the patients. Preservation of the anal transitional zone by the double-stapling technique does not improve functional results when compared to endoanal mucosectomy or intersphincteric resection. Impairment of continence is caused by damage of the internal sphincter with consecutive decrease of the pouch-anal pressure gradient. Despite altered reflex activity, stool discrimination is preserved in most patients. The loss of colonic water and electrolyte absorption is compensated by decreased renal excretion. Alterations in bile acid metabolism are lower after IPAA than after ileostomy. Bacterial overgrowth may lead to deterioration of the functional results.

UI MeSH Term Description Entries
D011183 Postoperative Complications Pathologic processes that affect patients after a surgical procedure. They may or may not be related to the disease for which the surgery was done, and they may or may not be direct results of the surgery. Complication, Postoperative,Complications, Postoperative,Postoperative Complication
D003093 Colitis, Ulcerative Inflammation of the COLON that is predominantly confined to the MUCOSA. Its major symptoms include DIARRHEA, rectal BLEEDING, the passage of MUCUS, and ABDOMINAL PAIN. Colitis Gravis,Idiopathic Proctocolitis,Inflammatory Bowel Disease, Ulcerative Colitis Type,Ulcerative Colitis
D005242 Fecal Incontinence Failure of voluntary control of the anal sphincters, with involuntary passage of feces and flatus. Bowel Incontinence,Fecal Soiling,Incontinence, Bowel,Incontinence, Fecal,Soilings, Fecal
D005500 Follow-Up Studies Studies in which individuals or populations are followed to assess the outcome of exposures, procedures, or effects of a characteristic, e.g., occurrence of disease. Followup Studies,Follow Up Studies,Follow-Up Study,Followup Study,Studies, Follow-Up,Studies, Followup,Study, Follow-Up,Study, Followup
D006801 Humans Members of the species Homo sapiens. Homo sapiens,Man (Taxonomy),Human,Man, Modern,Modern Man
D000714 Anastomosis, Surgical Surgical union or shunt between ducts, tubes or vessels. It may be end-to-end, end-to-side, side-to-end, or side-to-side. Surgical Anastomosis,Anastomoses, Surgical,Surgical Anastomoses
D016737 Proctocolectomy, Restorative A surgical procedure involving the excision of the COLON and RECTUM and the formation of an ILEOANAL RESERVOIR (pouch). In patients with intestinal diseases, such as ulcerative colitis, this procedure avoids the need for an OSTOMY by allowing for transanal defecation. Coloproctectomy, Restorative,Ileal Pouch Anal Anastomosis,Proctocolectomy,Total Proctocolectomy,Total Proctocolectomy with Ileal Pouch Anal Anastomosis,Proctocolectomies,Proctocolectomy, Total,Restorative Coloproctectomies,Restorative Coloproctectomy,Restorative Proctocolectomies,Restorative Proctocolectomy,Total Proctocolectomies

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