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Between weeks 10 and 20 of gestation, there are rapid and opposing changes in blood levels of two hormones produced by the syncytiotrophoblast; hPL increases and hCG decreases. In this study, the relationship between these two changing hormone levels was examined, rather than the serum concentrations themselves, as a potential test for placental maturation. The relationship between the hCG and hPL concentrations and GA determined in a selected group of patients was described by the following equation: GA (in days)=97.3 + 24.8 ln [hPL]-14.5 LN [HCG]. The endocrine evaluation of placental maturation by comparison of [hCG] and [hPL] in early pregnancy shows promise as a simple, safe, and inexpensive clinical tool for GA assessment.
L L Peeters, and
J A Lemons, and
G D Niswender, and
F C Battaglia
January 1974,
Journal of perinatal medicine,
L L Peeters, and
J A Lemons, and
G D Niswender, and
F C Battaglia
October 1983,
Nihon Sanka Fujinka Gakkai zasshi,
L L Peeters, and
J A Lemons, and
G D Niswender, and
F C Battaglia
October 1971,
Diabetes,
L L Peeters, and
J A Lemons, and
G D Niswender, and
F C Battaglia
July 1968,
Obstetrics and gynecology,
L L Peeters, and
J A Lemons, and
G D Niswender, and
F C Battaglia
April 1982,
The Journal of cell biology,
L L Peeters, and
J A Lemons, and
G D Niswender, and
F C Battaglia
November 1972,
Harefuah,
L L Peeters, and
J A Lemons, and
G D Niswender, and
F C Battaglia
February 1976,
Journal of obstetrics and gynaecology of India,
L L Peeters, and
J A Lemons, and
G D Niswender, and
F C Battaglia
December 1987,
The Journal of clinical endocrinology and metabolism,
L L Peeters, and
J A Lemons, and
G D Niswender, and
F C Battaglia
January 1993,
Acta cytologica,
L L Peeters, and
J A Lemons, and
G D Niswender, and
F C Battaglia
October 1984,
The Tohoku journal of experimental medicine,
