-transparent.png){kind=logo}
Pollution and industrial practices result in concentrations of metals and other environmental agents that are related to environmental toxicity. A rat bioassay was utilized for the identification of toxic effects of cadmium intake. This demonstrated increased total urinary proteins and increased kidney weights in rats exposed to CdCl2 for 7 days, in drinking water (100 mg/L). Serum creatinine, total and direct bilirubin concentrations and alanine transaminase activity were increased in Cd-exposed rats, indicating renal and hepatic toxicity. It was also observed that lipoperoxide concentrations were increased, while Cu-Zn superoxide dismutase activity was decreased in rats treated with cadmium. This indicated that the renal and hepatic toxicity induced by cadmium involved superoxide radicals.
E L Novelli, and
E P Vieira, and
N L Rodrigues, and
B O Ribas
January 1984,
Drug and chemical toxicology,
E L Novelli, and
E P Vieira, and
N L Rodrigues, and
B O Ribas
January 2004,
Journal of environmental biology,
E L Novelli, and
E P Vieira, and
N L Rodrigues, and
B O Ribas
January 1987,
The Journal of pharmacology and experimental therapeutics,
E L Novelli, and
E P Vieira, and
N L Rodrigues, and
B O Ribas
February 2008,
Pediatric nephrology (Berlin, Germany),
E L Novelli, and
E P Vieira, and
N L Rodrigues, and
B O Ribas
October 2021,
Saudi journal of biological sciences,
E L Novelli, and
E P Vieira, and
N L Rodrigues, and
B O Ribas
June 1982,
Toxicology letters,
E L Novelli, and
E P Vieira, and
N L Rodrigues, and
B O Ribas
January 1987,
Journal of toxicology and environmental health,
E L Novelli, and
E P Vieira, and
N L Rodrigues, and
B O Ribas
June 1990,
Indian journal of biochemistry & biophysics,
E L Novelli, and
E P Vieira, and
N L Rodrigues, and
B O Ribas
March 2016,
Pathophysiology : the official journal of the International Society for Pathophysiology,
E L Novelli, and
E P Vieira, and
N L Rodrigues, and
B O Ribas
October 1991,
Journal of pharmacobio-dynamics,
